tag:blogger.com,1999:blog-8964719845369935777.post8454218076489159104..comments2024-03-27T21:23:40.339-04:00Comments on Chemjobber: Process Wednesday: active HF decontamination solutionsChemjobberhttp://www.blogger.com/profile/15932113680515602275noreply@blogger.comBlogger9125tag:blogger.com,1999:blog-8964719845369935777.post-79606976602059565622013-08-01T17:17:23.695-04:002013-08-01T17:17:23.695-04:00FDA/GMP? I dunno. FDA/GMP? I dunno. Chemjobberhttps://www.blogger.com/profile/15932113680515602275noreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-70309731019658387842013-08-01T16:50:44.950-04:002013-08-01T16:50:44.950-04:00Doesn't look like HEXAFLUORINE® solution is co...Doesn't look like HEXAFLUORINE® solution is commercially available in the US. What is that all about?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-49017784850641687132012-04-05T03:43:48.332-04:002012-04-05T03:43:48.332-04:00Shouldn't you have to disclose the contents of...Shouldn't you have to disclose the contents of your product/drug/treatment in order to be published in a scientific journal? Otherwise, how can the product be evaluated thoroughly?Paulhttp://blog.chembark.comnoreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-64476026297099824662012-04-04T21:04:59.576-04:002012-04-04T21:04:59.576-04:00Uh, does having "specific binding sites for b...Uh, does having "specific binding sites for both the H+ and F- ions" make much sense when the pKa is only 3 or so?<br /><br />Conventional wisdom is that HF is deadly because it doesn't dissociate. It makes its way through tissue and bone all the time making insoluble CaF2.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-38532865098817831392012-04-04T20:26:23.656-04:002012-04-04T20:26:23.656-04:00Every time I worked with HF, I considered eating a...Every time I worked with HF, I considered eating a tube of Calgonate just as a precaution.Matthttp://sciencegeist.netnoreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-80856782760387070942012-04-04T14:48:45.602-04:002012-04-04T14:48:45.602-04:00It appears that the JCHAS article appears to be th...It appears that the JCHAS article appears to be the latest salvo between the Hexafluorine articles and the Swedish group above. Here's a response from the HexF people to the above cited Swedish paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116720/?tool=pubmed<br /><br />I suppose it boils down to this: if you work with 70% HF, you need to have decided already what the appropriate treatment is. It sounds like you have less than 3 minutes before damage sets in. <br /><br />Pop quiz, hotshot -- what are you going to do?Chemjobberhttps://www.blogger.com/profile/15932113680515602275noreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-62963164225703964072012-04-04T13:46:56.268-04:002012-04-04T13:46:56.268-04:00Relevant I guess:
http://www.ncbi.nlm.nih.gov/pubm...Relevant I guess:<br />http://www.ncbi.nlm.nih.gov/pubmed/15461243<br />"CONCLUSION:<br />In this experimental study, decontamination with Hexafluorine was not more effective than water rinsing in reducing electrolyte disturbances caused by dermal exposure to hydrofluoric acid."<br /><br />Poor rats though.Pentamethylnoreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-51190697629235909102012-04-04T11:56:20.546-04:002012-04-04T11:56:20.546-04:00Looks like hexafluorine could be EDTA and Aluminum...Looks like hexafluorine could be EDTA and Aluminum Nitrate? <br />French patent FR2604900 "Physiological solution for washing parts of the human body which have come into contact with hydrofluoric acid and concentrate for preparing it"<br />http://worldwide.espacenet.com/publicationDetails/claims;jsessionid=E8A857FD2FE5085A8F618F06A0BA53E0.espacenet_levelx_prod_3?CC=FR&NR=2604900A1&KC=A1&FT=D&ND=&date=19880415&DB=&&locale=en_EPBarneyhttps://www.blogger.com/profile/10870055736793776057noreply@blogger.comtag:blogger.com,1999:blog-8964719845369935777.post-50188578167483453782012-04-04T10:31:41.682-04:002012-04-04T10:31:41.682-04:00Just googling a little bit for fluoride chelation ...Just googling a little bit for fluoride chelation suggests that various boran compounds are used. Regardless, it still seems to be very effective and I'm glad to hear it as usually HF burns lead to something <a href="http://www.nejm.org/doi/full/10.1056/NEJMicm055763" rel="nofollow">like this.</a><br /><br />(In case the hyperlink isn't active: http://www.nejm.org/doi/full/10.1056/NEJMicm055763)Johnhttps://www.blogger.com/profile/04412324900423436763noreply@blogger.com