To answer Derek's question in terms of the San Diego biotech industry (I know that he was focusing on the SF Bay Area), it ain't looking good, with the number of job ads in the San Diego local ACS section newsletter staying flat. Again, I'm aware that this is a poor proxy at best for the overall state of the California biotech economy, but it's what I got.
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looks like Blogger doesn't work with anonymous comments from Chrome browsers at the moment - works in Microsoft Edge, or from Chrome with a Blogger account - sorry! CJ 3/21/20