I haven't seen the Sigma-for-TMS before, either, if that's what you mean. The original paper just has it as an R group. Taber's personal code or is this catching on somewhere?
I wonder if was a simply space issue as TMS blocked ring bonds, if so assume text or scheme legend in paper defined it that way since R is classically used for alkyl and carbon fragments. Alternatively I associate Sigma with "Sum of" math symbol therefore not clear what else would be the besides TMS but this could be representing more than one protecting group is observed?
I'm all for it; some of the silyl protecting groups can get rather ridiculous (TBDPSCl anyone?), so abbreviations are always appreciated as long as they're defined.
looks like Blogger doesn't work with anonymous comments from Chrome browsers at the moment - works in Microsoft Edge, or from Chrome with a Blogger account - sorry! CJ 3/21/20
I haven't seen the Sigma-for-TMS before, either, if that's what you mean. The original paper just has it as an R group. Taber's personal code or is this catching on somewhere?
ReplyDeleteI think I've seen sigma for silyl group before but not often - maybe he used it because you can't fit TMS easily in that spot in the structure.
ReplyDeleteI wonder if was a simply space issue as TMS blocked ring bonds, if so assume text or scheme legend in paper defined it that way since R is classically used for alkyl and carbon fragments. Alternatively I associate Sigma with "Sum of" math symbol therefore not clear what else would be the besides TMS but this could be representing more than one protecting group is observed?
ReplyDeleteI'm all for it; some of the silyl protecting groups can get rather ridiculous (TBDPSCl anyone?), so abbreviations are always appreciated as long as they're defined.
ReplyDeleteIt's rare, but I've seen the sigma symbol used as a shorthand for TMS.
ReplyDelete