Research Scientist II - Organic Chemistry (Ph.D. w/"3+ years of research experience beyond postdoctoral training in an academic or industrial setting")
We are looking for a highly motivated and talented chemist within CDoT to support advancement of compounds from PRISM screening. The PRISM multiplex screening platform efforts are yielding many hits with provocative predictive biomarkers and patterns of sensitivity. This position will be part of a multidisciplinary team challenged with identifying the targets and mechanism of action of these hit compounds, and advancing the compounds to later stages of drug discovery.
Ideally you will have experience establishing SAR for chemical probes and having contributed to project teams at early stages from Target and Hit Identification through Lead Optimization. You will work closely with other chemists, cell biologists, biochemists, structural and biophysical scientists and pharmacologists. Having dual reporting structures into Chemistry and Translation Science, you will play a key role in driving projects forward within CDoT at the Broad Institute.Also, this Group Leader position (Ph.D., w/7+ years of research experience in an industrial setting):
We are looking for a highly motivated scientist to lead and mentor a team of medicinal chemists focused on discovering novel small molecule therapeutics across a diverse disease portfolio. The successful candidate will join The Center for the Development of Therapeutics and lead a team of professional scientists at the interface of industry and academia.
The candidate will work closely with biochemists, structural and biophysical scientists, cell biologists and pharmacologists, to rapidly progress therapeutic projects in partnership with academic scientists and industrial partners. The successful applicant will have the unique opportunity to impact both the strategy and execution of multiple therapeutic programs driven by the novel genetic and biological insights being discovered at the Broad Institute.More Broad Institute positions here. Best wishes to those interested.