Friday, July 20, 2018

View From Your Hood: distant baseball edition

Boston University
Credit: @chemtoolman
From @chemtoolman:

"You can just make out Fenway Park in the distance."

(got a View from Your Hood submission? Send it in (with a caption and preference for name/anonymity, please) at chemjobber@gmail.com; will run every other Friday.) 

The most useless career trope: "[insert major here] can do everything"

The American Historical Association last week released a comprehensive snapshot of the entire discipline’s Ph.D. recipients. The project, Where Historians Work, tries to track where all of the 8,500 people who earned a doctorate from 2004 to 2013 landed jobs. About 7 percent of the recipients could not be found.... 
...Critics of the value of a history Ph.D. may find fodder in the history association’s project. Hover over some of the tiniest bubbles on an interactive slide, those representing just a single person, and you’ll see examples of people who may not have needed their Ph.D. for their current jobs: a rental-car clerk. A maintenance worker. An actor. A postal worker. 
But the biggest bubbles tell a more hopeful story about the utility of a history Ph.D. The data show that those who earned history Ph.D.s in that time include 174 chief executives, 363 higher-education administrators, 320 nonprofessors doing history, 57 curators, and 82 editors. The point: History Ph.D.s don’t just stay in academe. They are everywhere.
I admire this survey, and I encourage each field to do more of them. However, I find this trope of "they are everywhere" to be completely useless. Rather than saying "this is what you can do" or worse yet, "here is a story of one history Ph.D. who succeeded", I think it's far more useful to tell students and potential students "this is what you are likeliest to do, and here are the statistics to back that up."

What do they actually do? If you read the story, it sure looks like most of them end up at 4 year schools, either on the tenure-track (47%) or not (13%). Some of them go into higher ed administration (6%), the private sector (7%), government (7%) and non-profits (4%).

Here's what I think the study is missing: wages. What are the wages for these graduates? Until we know what the wages for the people are, there can be no economic conclusions drawn about this group of people. (Also, underemployment, but wages first.) 

Thursday, July 19, 2018

The Medicinal Chemist Jobs List: 138 positions

The Medicinal Chemist Jobs list (curated by Joel Walker and myself)  has 138 positions.

Want to help out? Here's a Google Form to enter positions, but if you want to do the traditional "leave a link in the comments", that works, too.

Want to chat about medchem positions? Try the open thread.

Positions I'm not including: positions outside the United States, computational positions (this will likely change), academic positions (likely never.)

The Computational Drug Discovery Chemistry Jobs List: 20 positions

The Computational Drug Discovery Chemistry Jobs List has 20 positions. This list is curated by Joel Walker. 

22 new positions at Organic Chemistry Jobs

Over at Common Organic Chemistry, there's 22 new positions posted for July 17.

The Process Chemistry Jobs List: 175 positions

The Process Chemistry Jobs List has 175 positions.

Want to help? Here's a form to fill out.

Want to chat process jobs? Try the open thread. 

Wednesday, July 18, 2018

Warning Letter of the Week: recycling consumables edition

A dispatch from the Center for Drug Evaluation and Research to the Managing Director of Claris Injectables Ltd. in Gujarat, India: 
1.    Your firm failed to thoroughly investigate any unexplained discrepancy or failure of a batch or any of its components to meet any of its specifications, whether or not the batch has already been distributed (21 CFR 211.192). 
Your firm invalidated out-of-specification (OOS) results without adequate investigation and scientific justification. Examples include: 
....In March, 2017, you obtained OOS results for the [redacted] impurity during stability testing of [redacted] injection batches [redacted]. You suspected the analyst may have incorrectly rinsed the HPLC vials. New samples prepared and tested by a second analyst using both the original column and a new column, as well as old and new vials, also yielded OOS results. Although you lacked sufficient evidence, your investigation concluded that the OOS results were due to sample vial contamination. You invalidated the OOS results after obtaining passing results from testing retain samples.
Rinsing HPLC vials??!?!?

(Someone who does science in the United States probably has no idea as to the constraints around consumables in the developing world. But still!)

Odd approach to peer review

Also in this week's C&EN, a pretty remarkable experiment from eLife (article by Katherine Sanderson): 
The life sciences journal eLife is trying out a radical approach to peer review. Rather than deciding whether to publish a paper after peer review, an editor’s decision to send a paper for peer review will be a commitment to eventually publish it. The trial is optional and aims to recruit 300 papers. In the trial, the editor and referees will agree on what they want authors to address.  
The authors can then make revisions, including more experiments; respond to criticisms; or withdraw the paper completely. The referee reports, editor’s decision letter, and authors’ response will be published alongside the final article. Reviewers can choose whether to remain anonymous.  
The aim is to give more power to authors, say eLife editors Mark Patterson and Randy Schekman in an editorial. They also hope it will strengthen the review process, with referees gaining a reputation for the advice they give. Observers welcome the trial with caution. Raghuveer Parthasarathy, a physicist from the University of Oregon, worries that journal editors sifting through initial submissions are given more power. “It may bias the system further towards flashy papers from well-connected authors,” he says.
This is a pretty interesting experiment, and it will be interesting to see if it produces anything sustainable... 

This week's C&EN

A few articles from this week's issue of Chemical and Engineering News:

Tuesday, July 17, 2018

The 2019 Chemistry Faculty Jobs List: 30 positions

The 2019 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 30 positions.

Want to help out? Here's a Google Form to enter positions.

Want to talk anonymously? Have an update on the status of a job search? Try the open thread.

Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

Please fill out the 2017-2018 Faculty Search Survey

In the interests of understanding the results of this year's academic recruiting, I have created an unscientific survey. I will be sharing results as they come in.

If you were a faculty candidate during the 2017-2018 academic year, please fill out this survey so we can get a better picture of the experience of faculty candidates this past year.

Please leave suggestions for improvements for the survey (and the List!) in the comments. 

The Academic Staff Jobs List: 25 positions

The Academic Staff Jobs list has 25 positions.

This list is curated by Sarah Cady. It targets:
  • Full-time STAFF positions in a Chem/Biochem/ChemE lab/facility at an academic institution/natl lab
  • Lab Coordinator positions for research groups or undergraduate labs 
  • and for an institution in Canada or the United States
Want to help out? Here's a Google Form to enter positions.

Want to chat about staff scientist positions? Try the open thread.

Monday, July 16, 2018

Chinese plant explosion kills 19

BEIJING — At least 19 people have been killed and a dozen injured after a chemical plant exploded in southwest China, engulfing the plant in flames and throwing a thick plume of smoke into the sky. 
The explosion erupted in an industrial park in Jiangan County, Sichuan Province, at about 6:30 p.m. on Thursday, the China News Service reported. Intense fires gutted a new-looking, three-story production building belonging to the Yibin Hengda Science and Technology Company, and windows of nearby buildings were shattered, a Sichuan news service said. 
“I heard an enormous explosion, enormous, and felt tremors,” Liu Ping, an official in charge of the industrial park, told a Chinese news website. “We’re now checking DNA to confirm the list of fatalities.” 
China’s grim record of accidents in factories and mines has improved in recent years, according to government statistics. They showed that 38,000 people died in work-related accidents last year, a fall of 12 percent from 2016.
Sounds like it was a methanol plant, which would offer plenty of risk of explosion. Best wishes to those involved. 

Friday, July 13, 2018

Nitrile gloves

A list of small, useful things (links): 
An open invitation to all interested in writing a blog, a hobby that will bring you millions thousands hundreds tens of dollars joy and happiness. Send me a link to your post, and I'd be happy to put it up.

Have a good weekend!

Are you having more difficulty in sourcing chemicals?

"Finally, we have found the Lost City of Acrolein!"
Credit: cageclub.me
This was an interesting comment by Dan Singleton at Texas A&M about the difficulty of sourcing basic organic chemicals. (Recently, he had difficulty in ordering acrolein, which is a bit of a surprise.)

Here's a comment about the difficulty in sourcing lithium powder (isn't there a Collum prep about how to make lithium powder? Does Rieke sell that? Either way, I'd rather buy that than make it.)

I haven't noticed too much difficulty in ordering compounds these days (at least in the 100 gram range.) Now tons of compound? I think it's always hard.

What's been your experience with finding lab-scale quantities of typical organic chemicals? 

Thursday, July 12, 2018

The Medicinal Chemist Jobs List: 121 positions

The Medicinal Chemist Jobs list (curated by Joel Walker and myself)  has 121 positions.

Want to help out? Here's a Google Form to enter positions, but if you want to do the traditional "leave a link in the comments", that works, too.

Want to chat about medchem positions? Try the open thread.

Positions I'm not including: positions outside the United States, computational positions (this will likely change), academic positions (likely never.)

The Computational Drug Discovery Chemistry Jobs List: 20 positions

The Computational Drug Discovery Chemistry Jobs List has 20 positions. This list is curated by Joel Walker. 

15 new positions at Organic Chemistry Jobs

Over at Common Organic Chemistry, there's 10 new positions posted for July 9 and 5 positions posted on July 5.

The Process Chemistry Jobs List: 175 positions

The Process Chemistry Jobs List has 175 positions.

Want to help? Here's a form to fill out.

Want to chat process jobs? Try the open thread. 

Wednesday, July 11, 2018

Warning Letter of the Week: throw it all in there edition

A note from the Center for Drug Evaluation and Research to the General Manager of Foshan Jinxiong Technology Co., Ltd.: 
4.    Your firm failed to prepare batch production and control records with complete information relating to the production and control of each batch of drug product produced (21 CFR 211.188).
You lacked complete information related to the production and control of each lot. For example, you failed to have specific identification for each  lot of component, and production equipment, used in manufacturing. You also failed to have unique lot or control numbers for the distributed drug product. You provided our investigator with a list of more than [redacted] batches manufactured in 2017 that lacked this basic information.

In your response, you described your new lot numbering system and how you revised your production records. You also provided a copy of the revised production record.
Figuring out a way to accurately and robustly number manufacturing batches is a non-trivial task. Not numbering them at all is a pretty bold and simple solution! 

It's good to be Andy

Long-time Chemjobber bugaboo Andrew Liveris (and retired Dow CEO) had a few perks (article by Alex Tullo):
Dow Chemical will pay the U.S. Securities & Exchange Commission $1.75 million for failing to report $3.0 million in perks to former CEO Andrew N. Liveris, who retired on July 1. Among the benefits, SEC says, were travel to outside board meetings, sporting events, and personal activities; club memberships; and a board membership fee for a charity. SEC says Dow didn’t have the right system in place for sorting out and reporting such expenses.
There's a software package I'd like to expense with my employer, maybe I could sneak a few Padres tickets in there too....

This week's C&EN

A few articles from this week's issue of Chemical and Engineering News:

Tuesday, July 10, 2018

The 2019 Chemistry Faculty Jobs List: 18 positions

The 2019 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 18 positions.

Want to help out? Here's a Google Form to enter positions.

Want to talk anonymously? Have an update on the status of a job search? Try the open thread.

Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

Postdoctoral position: Reed College, Portland, OR

From the inbox, a postdoctoral position: 
We invite applications for a postdoctoral position in organometallic chemistry at Reed College under the supervision of Dr. Miriam Bowring.  This research position focuses on organometallic mechanisms, synthesis, and catalysis. 
The postdoctoral researcher will develop homogeneous organometallic reactions with late transition metals for probing the causes and effects of large kinetic isotope effects. The position requires strong communication skills, since this work involves collaboration and supervision of undergraduate research projects.  Applicants with a desire to mentor undergraduates, work independently, pursue external funding, and become an active member of the Reed community are preferred.
Link to ad here. Best wishes to those interested.  

Faculty position: Reed College, fall 2019, Portland, OR

From the inbox, a tenure track opening at Reed College:
Reed College is hiring a tenure-track chemist and we are interested in hearing from candidates with a broad range of background and training. 
Please apply or share our ads with anyone who has interest in well-supported research and teaching at an undergraduate level. We value diversity and encourage applications from underrepresented groups.
Link to ad here. Best wishes to those interested.

Please fill out the 2017-2018 Faculty Search Survey

In the interests of understanding the results of this year's academic recruiting, I have created an unscientific survey. I will be sharing results as they come in.

If you were a faculty candidate during the 2017-2018 academic year, please fill out this survey so we can get a better picture of the experience of faculty candidates this past year.

Please leave suggestions for improvements for the survey (and the List!) in the comments. 

The Academic Staff Jobs List: 25 positions

The Academic Staff Jobs list has 25 positions.

This list is curated by Sarah Cady. It targets:
  • Full-time STAFF positions in a Chem/Biochem/ChemE lab/facility at an academic institution/natl lab
  • Lab Coordinator positions for research groups or undergraduate labs 
  • and for an institution in Canada or the United States
Want to help out? Here's a Google Form to enter positions.

Want to chat about staff scientist positions? Try the open thread.

Monday, July 9, 2018

Colorado State biochemistry professor fakes job offer, gets caught

Via Twitter and Denver's local CBS station, quite the story out of Colorado State University (article by Mark Ackerman)
FORT COLLINS, Colo. (CBS4) – A former professor at Colorado State University is facing a felony charge for fabricating an outside job offer to improve his status at CSU. Professor Brian McNaughton, 40, ran the McNaughton Lab, a biochemistry research group at CSU. 
He is now charged with attempt to influence a public official, for presenting his employers with a fictitious offer letter from the University of Minnesota in order to get more money from CSU. 
The falsification was determined through a series of emails between leaders of the two schools. CBS4 obtained the conversations through a Colorado Open Records Act Request. 
“It is my understanding this letter is simply a fake,” wrote Dr. Dan Bush, Vice Provost for Faculty Affairs at CSU. “Needless to say we are shocked and dismayed that one of our faculty would fabricate such a letter to advance the status at CSU.” “Quite shocking indeed!” wrote Tom Hays, Professor at University of Minnesota. “I can confirm that I did not write, nor sign an offer letter to Brian McNaughton during my interim term (2014-2015) as Dean of College of Biological Sciences at the University of Minnesota.”
McNaughton resigned his position at CSU. In a letter to the Dean, McNaughton apologized for an “enormous mistake.” He wrote that he got the idea to fake the outside offer from colleagues. 
“It was openly stated that multiple former CSU faculty (now either dead or no longer affiliated with CSU) lied about an outside offer as a mechanism to improve their salary,” McNaughton wrote. “I’m not excusing it, and I’m not excusing my own actions, but these factors are real.”
From conversations with professors at research universities, I have heard departments basically demand an outside offer before considering a pay raise. That said, I think this is reasonably common in many industries (particularly financially-related industries?). I imagine that the demanded raises are relatively large (greater than 10%?)

I do think it is interesting that this ultimately got caught - I wonder when that happened? I suspect that non-email conversations were how this was uncovered, i.e. one department member saying to a friend in the other one, "say, I heard you guys made Prof. McNaughton an offer?" and the response was "uh, what offer?

It's also interesting that Prof. McNaughton claims that faking outside offers was common - I would love to know the backstory on that claim as well...

UPDATE: Anon838 notes The Chronicle of Higher Education has McNaughton's letter. Might offer some insight into his state of mind.

Also, the article makes a vague comment about felony charges. Who is pressing charges? The university? 

Friday, July 6, 2018

I'll never eat chili again

Credit: Wikimedia
A recent conversation with a friend was about food in graduate school. They were pretty glad to be done with eating ramen and other various inexpensive meals.

What was your go-to meal? Mine was chili. I was a big fan of making a huge pot and freezing it and eating chili for two weeks or so. (Did I mention that I lived alone in graduate school?) 

This week's C&EN

A few of the articles from this week's issue of Chemical and Engineering News:

Thursday, July 5, 2018

The Medicinal Chemist Jobs List: 119 positions

The Medicinal Chemist Jobs list (curated by Joel Walker and myself)  has 119 positions.

Want to help out? Here's a Google Form to enter positions, but if you want to do the traditional "leave a link in the comments", that works, too.

Want to chat about medchem positions? Try the open thread.

Positions I'm not including: positions outside the United States, computational positions (this will likely change), academic positions (likely never.)

The Computational Drug Discovery Chemistry Jobs List: 20 positions

The Computational Drug Discovery Chemistry Jobs List has 20 positions. This list is curated by Joel Walker. 

18 new positions at Organic Chemistry Jobs

Over at Common Organic Chemistry, there's 11 new positions posted for July 1 and 7 positions posted on June 26. 

The Process Chemistry Jobs List: 168 positions

The Process Chemistry Jobs List has 168 positions.

Want to help? Here's a form to fill out.

Want to chat process jobs? Try the open thread. 

Wednesday, July 4, 2018

Independence Day



It's Independence Day in the United States, which is a national holiday. We'll see you tomorrow!

Tuesday, July 3, 2018

Faculty position: Reed College, fall 2019, Portland, OR

From the inbox, a tenure track opening at Reed College:
Reed College is hiring a tenure-track chemist and we are interested in hearing from candidates with a broad range of background and training. 
Please apply or share our ads with anyone who has interest in well-supported research and teaching at an undergraduate level. We value diversity and encourage applications from underrepresented groups.
Link to ad here. Best wishes to those interested.

The 2019 Chemistry Faculty Jobs List: 12 positions

The 2019 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 12 positions.

Want to help out? Here's a Google Form to enter positions.

Want to talk anonymously? Have an update on the status of a job search? Try the open thread.

Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

Please fill out the 2017-2018 Faculty Search Survey

In the interests of understanding the results of this year's academic recruiting, I have created an unscientific survey. I will be sharing results as they come in.

If you were a faculty candidate during the 2017-2018 academic year, please fill out this survey so we can get a better picture of the experience of faculty candidates this past year.

Please leave suggestions for improvements for the survey (and the List!) in the comments. 

The Academic Staff Jobs List: 25 positions

The Academic Staff Jobs list has 25 positions.

This list is curated by Sarah Cady. It targets:
  • Full-time STAFF positions in a Chem/Biochem/ChemE lab/facility at an academic institution/natl lab
  • Lab Coordinator positions for research groups or undergraduate labs 
  • and for an institution in Canada or the United States
Want to help out? Here's a Google Form to enter positions.

Want to chat about staff scientist positions? Try the open thread.

Friday, June 29, 2018

Peroxide test strips

A list of small, useful things (links):
An open invitation to all interested in writing a blog, a hobby that will bring you millions thousands hundreds tens of dollars joy and happiness. Send me a link to your post, and I'd be happy to put it up.

Have a good weekend!

Maybe it's the working conditions?

There's a trucker shortage, the Washington Post reports: 
...As the nation faces a historically low level of unemployment, trucking companies are doing what economists have said firms need to do to attract and retain workers: They’re hiking pay significantly, offering bonuses and even recruiting people they previously wouldn’t have considered. 
But it’s not working. The industry reports a growing labor shortage — 63,000 open positions this year, a number expected to more than double in coming years — that could have wide-ranging impacts on the U.S. economy. 
In interviews with more than 60 trainees, recruiters and people who explored trucking but decided not to take the job, most said they feel that higher pay will help but that the industry’s problems are much deeper than that. 
Trucking remains one of the most dangerous professions in the country. There were more than 1,000 fatalities among motor vehicle operators in 2016, according to the Labor Department, meaning being a commercial driver is nearly eight times as deadly as being a law enforcement officer. 
...Trucking jobs require people to leave their families for weeks at a time and live in a small “cabin” with a hard bed. Divorces are common, veteran drivers say, and their children forget them. A life on the road is often costly and unhealthy. Drivers sit for hours a day in diesel trucks and pull into truck stops that typically serve greasy hot dogs and chili. 
Weight gain and heart disease are common, says Gordon Zellers, an Ohio physician who spends half his time examining truckers and administering drug tests, which increasing numbers of CDL applicants fail. 
As it has trouble recruiting new workers, the industry also is struggling to hold on to drivers. Turnover in the trucking industry has skyrocketed to 94 percent, according to the American Trucking Associations, meaning most drivers at the major trucking companies don’t spend more than a year in their jobs. That reflects a combination of poaching and quitting....
That's some pretty intense turnover. I haven't thought about trucking yet....

The life of a trucker, long story short, seems miserable, especially the part about being away from your family for a month at a time. I was trying to figure out how much I would have to be paid to take a job as a trucker, i.e. the amount of money I would have to make before I would start to get tempted. It was many multiples of the $42k that the Bureau of Labor Statistics suggests that the median trucker makes. (I recognize that number is not the likely wage that a long-haul trucker makes.) 

Wednesday, June 27, 2018

Are there famous cases of sabotage in the chemical or pharma industries?

An odd story from Tesla Motors (via the New York Times): 
Now Tesla’s chief executive, Elon Musk, suspects his company might have a more unusual problem: sabotage. 
In an email sent to employees late Sunday night, Mr. Musk said a disgruntled worker had broken into the company’s computer systems in an attempt to disrupt manufacturing. 
“I was dismayed to learn this weekend about a Tesla employee who had conducted quite extensive and damaging sabotage to our operations,” he wrote. “This included making direct code changes to the Tesla Manufacturing Operating System under false usernames and exporting large amounts of highly sensitive Tesla data to unknown third parties.”
That seems problematic for Tesla - I wonder how long it will take to fix this issue? I imagine that there are relatively few situations where pharma or chemical industry insiders found themselves tempted enough to act on negative impulses... 

This week's C&EN

A few of the articles in this week's issue of Chemical and Engineering News:

    Tuesday, June 26, 2018

    The 2019 Chemistry Faculty Jobs List: 9 positions

    The 2019 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 9 positions.

    Want to help out? Here's a Google Form to enter positions.

    Want to talk anonymously? Have an update on the status of a job search? Try the open thread.

    Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

    The Academic Staff Jobs List: 25 positions

    The Academic Staff Jobs list has 25 positions.

    This list is curated by Sarah Cady. It targets:
    • Full-time STAFF positions in a Chem/Biochem/ChemE lab/facility at an academic institution/natl lab
    • Lab Coordinator positions for research groups or undergraduate labs 
    • and for an institution in Canada or the United States
    Want to help out? Here's a Google Form to enter positions.

    Want to chat about staff scientist positions? Try the open thread.

    Friday, June 22, 2018

    View From My Hood?: Shanghai edition

    (got a View from Your Hood submission? Send it in (with a caption and preference for name/anonymity, please) at chemjobber@gmail.com; will run every other Friday.)

    Thursday, June 21, 2018

    The Medicinal Chemist Jobs List: 182 positions

    The Medicinal Chemist Jobs list (curated by Joel Walker and myself)  has 182 positions.

    Want to help out? Here's a Google Form to enter positions, but if you want to do the traditional "leave a link in the comments", that works, too.

    Want to chat about medchem positions? Try the open thread.

    Positions I'm not including: positions outside the United States, computational positions (this will likely change), academic positions (likely never.)

    The Computational Drug Discovery Chemistry Jobs List: 20 positions

    The Computational Drug Discovery Chemistry Jobs List has 20 positions. This list is curated by Joel Walker. 

    22 new positions at Organic Chemistry Jobs

    Over at Common Organic Chemistry, there's 22 new positions posted for June 19.

    The Process Chemistry Jobs List: 166 positions

    The Process Chemistry Jobs List has 166 positions.

    Want to help? Here's a form to fill out.

    Want to chat process jobs? Try the open thread. 

    Wednesday, June 20, 2018

    What's Wrong with This Picture?: sodium azide edition

    I think you got it wrong, guys. 

    Lead follies

    In a very interesting paper in the Journal of Chemical Health and Safety titled "The state of the arts: Chemical Safety - 1937 to 2017" [1], longtime DCHAS-L correspondent and art/chemical safety expert Monona Rossol tells about her history in the arts and safety, including this rather hair-raising story:
    A number of sculpture students, including myself, got acute lead poisoning when we were taught to make "dripped lead sculpture". We melted junk yard lead indoors without ventilation, cast it into bars, and used an acetylene torch to remelt the bars and drip the lead into our molds. We thought we had some kind of flu that caused the vomiting and diarrhea. No one in the art department, including me at that time, knew that an invisible fume of tiny lead oxide particles is emitted into the air when lead melts. And since the first effects of lead exposure are to lower the IQ, it may explain why I still remained in art school. 
    Yikes! Artists do funny things for art.

    1. Rossol, M. "The state of the arts: Chemical safety - 1937 to 2017." J. Chem. Health Saf. 2018, 25 (2), 18-27.

    Warning Letter of the Week: fourth time's the charm edition

    A greeting from the Center for Drug Evaluation and Research to the chairman of the board of IDT Australia:
    2. Your firm failed to ensure that laboratory records included complete data derived from all tests necessary to assure compliance with established specifications and standards. (21 CFR 211.194(a)). Our review of your laboratory records revealed that you failed to report non-conforming test results on multiple occasions in multiple parts of your operations.

    Analytical TestingDuring testing of [redacted] exhibit batch [redacted] in March 2016, three consecutive identity test failures occurred. The fourth test passed and you reported this conforming result. You did not include the three failures in the data package submitted to the quality unit for review or your application submission for this product. You did not conduct an investigation into the non-conforming results. At the time of the inspection, you were unaware that your analysts had not reported the failing results to your quality unit for review.
    Surely those first three tests didn't mean anything.  

    Tuesday, June 19, 2018

    The 2019 Chemistry Faculty Jobs List: 8 positions

    The 2019 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 8 positions.

    Want to help out? Here's a Google Form to enter positions.

    Want to talk anonymously? Have an update on the status of a job search? Try the open thread.

    Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

    The Academic Staff Jobs List: 25 positions

    The Academic Staff Jobs list has 25 positions.

    This list is curated by Sarah Cady. It targets:
    • Full-time STAFF positions in a Chem/Biochem/ChemE lab/facility at an academic institution/natl lab
    • Lab Coordinator positions for research groups or undergraduate labs 
    • and for an institution in Canada or the United States
    Want to help out? Here's a Google Form to enter positions.

    Want to chat about staff scientist positions? Try the open thread.

    Monday, June 18, 2018

    Job posting: research scientist, Carbon Recycling International, Kopavogur, Iceland

    From the inbox, Carbon Recycling International is searching for a research scientist:
    Main responsibilities and tasks: 
    • Independent research on laboratory and plant scale
    • Catalyst development and testing 
    • Chemical synthesis 
    • Purification and analysis...
    M.S./Ph.D. in chemistry or chemical engineering desired. Link here. Best wishes to those interested. 

    This week's C&EN

    A few of the articles in this week's issue of Chemical and Engineering News

    Friday, June 15, 2018

    Pipette tips

    A list of small, useful things (links):
    An open invitation to all interested in writing a blog, a hobby that will bring you millions thousands hundreds tens of dollars joy and happiness. Send me a link to your post, and I'd be happy to put it up.

    Have a good weekend!

    Liquid hydrogen cyanide grenades?

    But it looks so innocuous!
    Credit: Reddit user why_da_herrrooo
    Via Twitter, this funny/scary Reddit post from a year ago, where someone posted a picture of this object on the right, and it was found to be a Japanese hydrogen cyanide grenade from World War II.  (emphasis mine):
    I let me uncle know what everyone said it probably is and he said he's surprised he's not dead. This being he said that the rubber seal had been disintegrating over the years that's why you can see flakes floating around in the picture, that the rubber seal that had been disintegrating into the bottle and he had just been re-sealing the sides with glue. He said he moved it into another location not near his house and will call some officials tomorrow on what to do with it. He's not too concerned in the meantime as he has had it on his shelf in his bedroom for the last 50 some years and nothing's happened yet.  
    Thank you all for the responses he was actually planning on opening it and switching the contents to a more secure container, that's why he actually showed it to me to see what his next "project" was. You all probably saved a life so I really appreciate it!
    Well, that would have been bad. Glad it worked out all right.  

    Thursday, June 14, 2018

    The Medicinal Chemist Jobs List: 173 positions

    The Medicinal Chemist Jobs list (curated by Joel Walker and myself)  has 173 positions.

    Want to help out? Here's a Google Form to enter positions, but if you want to do the traditional "leave a link in the comments", that works, too.

    Want to chat about medchem positions? Try the open thread.

    Positions I'm not including: positions outside the United States, computational positions (this will likely change), academic positions (likely never.)

    The Computational Drug Discovery Chemistry Jobs List: 15 positions

    The Computational Drug Discovery Chemistry Jobs List has 15 positions. This list is curated by Joel Walker. 

    19 new positions at Organic Chemistry Jobs

    Over at Common Organic Chemistry, there's 19 new positions posted for June 4.

    The Process Chemistry Jobs List: 166 positions

    The Process Chemistry Jobs List has 166 positions.

    Want to help? Here's a form to fill out.

    Want to chat process jobs? Try the open thread. 

    Wednesday, June 13, 2018

    Not a good mixer for drinks

    Credit: David Kochman
    Other potential warnings for a bottle of 2-mercaptoethanol:

    1. DOESN'T SMELL GOOD
    2. NOT A GOOD HAND LOTION
    3. DO NOT ADD TO CHEESE DIP

    Ed Breen, killer of moonshots

    Also in this week's C&EN, this is quite the article about Ed Breen, current CEO of DowDuPont (article by Alex Tullo): 
    DowDuPont CEO Ed Breen says he prefers small, short-term R&D projects that quickly yield marketable products to moonshots that are risky and more expensive. 
    Breen took over as DuPont CEO in November 2015 and quickly inked an agreement to merge with Dow Chemical. At the Bernstein Strategic Decisions Conference in New York City on May 31, Breen discussed his company’s R&D strategy. 
    Breen said that he scaled back ambitious projects as soon as he was in charge at DuPont. “When I got to the company, we killed almost all of what I’d call the moonshot projects,” he said. “And, by the way, the moonshots cost the most money. I didn’t feel comfortable with most of them.” 
    ...Additionally, in late 2015, Breen recast DuPont’s Central R&D organization, famous in the chemical industry for its devotion to long-term projects, into a smaller organization, Science & Innovation.
    Short-term profits first! I look forward to looking at his track record 5 or 10 years from now... 

    This week's C&EN

    A few of the articles from this week's issue of C&EN

    Tuesday, June 12, 2018

    The 2019 Chemistry Faculty Jobs List: 4 positions

    The 2019 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 4 positions.

    Want to help out? Here's a Google Form to enter positions.

    Want to talk anonymously? Have an update on the status of a job search? Try the open thread.

    Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

    The Academic Staff Jobs List: 25 positions

    The Academic Staff Jobs list has 25 positions.

    This list is curated by Sarah Cady. It targets:
    • Full-time STAFF positions in a Chem/Biochem/ChemE lab/facility at an academic institution/natl lab
    • Lab Coordinator positions for research groups or undergraduate labs 
    • and for an institution in Canada or the United States
    Want to help out? Here's a Google Form to enter positions.

    Want to chat about staff scientist positions? Try the open thread.

    Friday, June 8, 2018

    View From Your Hood: Berkeley sunset edition

    Credit: @christine_m_le
    Via Twitter user @christine_m_le: "Can’t get enough of these epic sunsets at @UCB_Chemistry."

    (got a View from Your Hood submission? Send it in (with a caption and preference for name/anonymity, please) at chemjobber@gmail.com; will run every other Friday.)

    Where do you go, in the middle of your career?

    Over at Wandering Scientist, Cloud is thinking and musing about her career:
    ...It isn't that my career is going badly... it is more that I feel like I've lost the plot of my career. For years, the goals I was aiming for were obvious. But right now, they aren't. I am unsure what I really want to aim for. That's OK: I have a good job at a good company, working with people I like. I don't necessarily see much scope for advancement at this particular company, but that may not actually be a problem. As one of my peer mentors pointed out today, there are other things I could do to get growth. 
    The question I have to answer is: growth toward what? That is less obvious to me right now. Strangely, I think I am OK with that, too. I don't have an urgent need to change anything. I might take a little time to think about what my long term goals should be, pick some of the more low key growth ideas my peer group came up with, coast along for a bit without any urgency on them, and see which things sprout...
    At this moment in my career, I don't feel the same way, in that I think I know what I am growing towards, and I know that there is a real, definite (and rather scary) set of diverging paths coming in the next three to five years. If we are successful, it will be good for us (and, I hope, good for my career.) But it could go poorly, and it wouldn't be good for us, or for me. 

    What do people in the middle of their careers do? Fake-it-til-you-make-it? Strategize constantly? Pick a goal and work towards it? Or do they just keep persisting? 

    (Oh, yeah, and how often do you have an existential crisis between 35 and 50? Once a year? Once a month?) 

    Thursday, June 7, 2018

    The Medicinal Chemist Jobs List: 168 positions

    The Medicinal Chemist Jobs list (curated by Joel Walker and myself)  has 168 positions.

    Want to help out? Here's a Google Form to enter positions, but if you want to do the traditional "leave a link in the comments", that works, too.

    Want to chat about medchem positions? Try the open thread.

    Positions I'm not including: positions outside the United States, computational positions (this will likely change), academic positions (likely never.)

    The Computational Drug Discovery Chemistry Jobs List: 15 positions

    The Computational Drug Discovery Chemistry Jobs List has 15 positions. This list is curated by Joel Walker. 

    15 new positions at Organic Chemistry Jobs

    Over at Common Organic Chemistry, there's 15 new positions posted for June 4.

    The Process Chemistry Jobs List: 161 positions

    The Process Chemistry Jobs List has 161 positions.

    Want to help? Here's a form to fill out.

    Want to chat process jobs? Try the open thread. 

    Wednesday, June 6, 2018

    What's the outlook for IP law?

    From the inbox, a good question and observation. First, what is the long-term outlook for intellectual property law for chemists (in terms of patent agent positions and IP lawyers?)

    On that note, it appears that there isn't much data. You will be amused to know that the Bureau of Labor Statistics sees lawyers growing at 8% for 2016-2026. (Chemists, readers of this blog will know, are expected to grow at a rate of 6% for the same time period.) Here's a BLS paper that doesn't really have much data about the field, but might be worth a perusal anyway. 


    2017: 2346
    2016: 2424
    2015: 2495
    2014: 2799
    2013: 2766
    2012: 3365
    2011: 2716
    2010: 3120
    2009: 3357
    2008: 3634
    2007: 3192
    2006: 2923
    2005: 2673

    Looks like we are in a local minima? (Sure can see a lot of activity during the Great Recession!) Hard to know what this means 10 years from now. 

    Anyone have a good suggestion of sites for contract synthesis work?

    An anonymous person writes in, asking if there are any collaboration sites for freelance synthetic work. Does Science Exchange or any of these other sites have places for chemists to hang out their shingles? 

    Tuesday, June 5, 2018

    The 2019 Chemistry Faculty Jobs List Start (3 positions) and Open Thread

    The 2019 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 3 positions.

    Want to help out? Here's a Google Form to enter positions.

    The 2018 Chemistry Faculty Jobs List finished with 552 positions.

    Want to talk anonymously? Have an update on the status of a job search? This will serve as the open thread.

    Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

    The 2018 Chemistry Faculty Jobs List (final number): 552 positions

    The final count for the 2018 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 552 positions.

    The 2017 Chemistry Faculty Jobs List finished with 590 positions.

    Does anyone want to guess as to whether or not the 2019 Faculty Jobs List will have more or fewer positions than 2018? I am taking the under, even as I feel that we were far more diligent in tracking down positions in 2018 than in 2017.

    Want to talk anonymously? Have an update on the status of a job search? Try the open thread.

    See Arr Oh's Chemistry Bumper Cars list for 2018 is here.

    Want to talk about starting your new group? That open discussion is here.

    Otherwise, all discussions are on the Chemistry Faculty Jobs List webforum.

    Postdoctoral position: synthetic organic chemistry, UNC Chapel Hill

    From the inbox, a postdoc at UNC:
    Synthetic organic chemist position focused on the design and  construction of novel molecules for selective dopamine modulation. Each scaffold under investigation appears to interact at allosteric sites not the dopamine binding site, a novel approach to dopamine regulation.  This project is a collaboration with the Sibley Lab (NIH/NINDS), who are responsible for all assays and screening. Thus, this position is dedicated to the development of new synthetic methods and routes to the target scaffolds and their application to construct further analogues.  Research is conducted within the highly collaborative environment of the UNC Center for Integrative Chemical Biology and Drug Discovery. http://frankowskilab.web.unc.edu/
    Best wishes to those interested. Full ad here. 

    The Academic Staff Jobs List: 25 positions

    The Academic Staff Jobs list has 25 positions.

    This list is curated by Sarah Cady. It targets:
    • Full-time STAFF positions in a Chem/Biochem/ChemE lab/facility at an academic institution/natl lab
    • Lab Coordinator positions for research groups or undergraduate labs 
    • and for an institution in Canada or the United States
    Want to help out? Here's a Google Form to enter positions.

    Want to chat about staff scientist positions? Try the open thread.

    Monday, June 4, 2018

    There's a cuvette shortage?

    Also in this week's C&EN, an apparent shortage of cuvettes (article by Marc Reisch): 
    High-end cuvettes—straight-sided clear containers used to hold analytical samples in spectrophotometers—are in short supply from the German manufacturer Hellma Analytics. So far, though, only a few people have noticed. 
    Evan Friedmann, vice president of Hellma’s U.S. distribution arm, says his firm is suffering from limited output of certain cuvettes designed for research. He chalks the problem up to delayed delivery of a new computer-controlled machine tool and strong demand for spectrophotometer accessories. “Hellma is currently seeing the highest order booking in our 96-year history,” he says. 
    Cuvettes are typically used in pairs and need to be optically matched, says instrumentation consultant Ellen Miseo. Scientists use cuvettes to place solutions into ultraviolet-visible or fluorescence spectrophotometers to measure concentrations. They range in price from under $100 to over $500 each. 
    Hellma has been struggling with the cuvette shortage since the end of 2017. In March, the company sent a letter to customers and distributors acknowledging a delay in the delivery of a new machine tool to its facility in Müllheim. It also noted a shortage of workers at the time “due to the nationwide flu epidemic.”
    Interesting that the article notes that the shortage really hasn't hit in the US.  

    This week's C&EN

    A few articles from this week's issue of Chemical and Engineering News:

    Friday, June 1, 2018

    ArkPharm proprietors arrested for fentanyl distribution

    Via Matthew Katcher, this story by Rick Kambic of the Pioneer Press (at the Chicago Tribune website)
    Two suburban residents appeared in federal court Thursday morning on charges related to the sale of fentanyl and fentanyl precursors over the internet using unlicensed businesses. 
    Wei Xu, 52, who goes by the alias “Scarlett Hsu,” lives in Vernon Hills and operated a business known as 1717 CheMall Corp. from a warehouse at 222 Terrace Drive, Mundelein, according to a news release from the U.S. attorney’s office. 
    A multi-jurisdictional task force led by the Drug Enforcement Administration raided 1717 CheMall Corp. late Wednesday. Employees of neighboring businesses posted photos of the activity on social media, but the U.S. attorney’s office was unable to disclose what was recovered from the warehouse. 
    Xu was charged with one count of knowingly distributing a controlled substance. Prosecutors said she used the company’s website to sell “fentanyl and other controlled substances” from the site’s “estore.” 
    Federal prosecutors say Liangfu “Larry” Huang, 53, of Northbrook, ran a business known as Ark Pharm Inc., which operated from a warehouse at 1840 Industrial Drive, Libertyville, until recently moving to 3860 N. Ventura Drive, Arlington Heights, according to the federal complaint. 
    Also via Matthew, check out the website.

    Looks like you can't buy fentanyl "for laboratory purposes only" and escape the long arm of the law. [Nods] Good to know. 

    40 mL vials

    A list of small, useful things (links):
    An open invitation to all interested in writing a blog, a hobby that will bring you millions thousands hundreds tens of dollars joy and happiness. Send me a link to your post, and I'd be happy to put it up.

    Have a good weekend!

    Thursday, May 31, 2018

    The Computational Drug Discovery Chemistry Jobs List: 15 positions

    The Computational Drug Discovery Chemistry Jobs List has 15 positions. This list is curated by Joel Walker. 

    The Medicinal Chemist Jobs List: 159 positions

    The Medicinal Chemist Jobs list (curated by Joel Walker and myself)  has 159 positions.

    Want to help out? Here's a Google Form to enter positions, but if you want to do the traditional "leave a link in the comments", that works, too.

    Want to chat about medchem positions? Try the open thread.

    Positions I'm not including: positions outside the United States, computational positions (this will likely change), academic positions (likely never.)