Thursday, April 4, 2024

Job posting: Associate Principal Investigator, Toxinology, Battelle National Biodefense Institute, Frederick, MD

Via C&EN Jobs: 


The National Biodefense Analysis and Countermeasures Center (NBACC) is a one-of-a-kind facility dedicated to defending the nation against biological threats. Its work supports DHS and National biodefense preparedness planning, response, emerging threat characterization and bioforensic analyses. It is the first national laboratory created by DHS in response to biodefense gaps identified following the Amerithrax attacks of 2001 and has been operated by the Battelle National Biodefense Institute (BNBI) since 2006. Since its inception, NBACC and its staff have filled critical shortfalls in our scientific knowledge of biological agents needed to protect the public and defend the Nation from biological threats, whether naturally occurring, accidental, or deliberate and provided federal law enforcement with scientific data to support the investigation and attribution of biocrimes and protection of the US bioeconomy.

NBACC includes two centers: the National Bioforensic Analysis Center (NBFAC), which conducts the technical analyses in support of federal law enforcement investigations, and the National Biological Threat Characterization Center (NBTCC), which conducts experiments and studies to obtain data required for a better understanding of biological vulnerabilities and hazards. Together these centers offer a unique national resource for understanding the risks posed by biological agents and emerging technologies to inform biodefense policy and response planning and the operational capability to support the investigation, prosecution, and prevention of biocrimes and bioterrorism.


Applies expertise in protein and peptide biochemistry in collaboration with a team of scientists in the NBTCC within the NBACC to perform Toxinology research that addresses specific questions of national significance in support of biodefense preparedness, response, and recovery. Areas of research include a range of topics related to the physical, biological, and/or pathological properties of toxin agents. Work will be performed in state-of-the-art laboratories. All facilities are fully staffed and equipped with a wide range of technologies required for biodefense and infectious disease research.


  • Requires a PhD (or equivalent) in a scientific discipline or engineering, and a minimum of 2 years related experience.
  • Requires expertise in one or more of the following:
    • Heterologous protein expression, purification, and characterization.
    • Solid phase peptide and protein synthesis, purification, and characterization.
    • Cell-based toxicity and/or electrophysiological assays.

Full ad here. Best wishes to those interested. 

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