C&EN: "An old cholesterol drug could help clear PFAS"

In Chemical and Engineering News, this news (article by Saima Sidik)

Paul Smith, a retired nurse anesthetist, has been contending with chronic lymphocytic leukemia since 2012, and his doctor suspects a tumor is forming in his pituitary gland. But despite the uncertainty about his health, a well-known cholesterol management drug is giving him a bit of hope.

Smith lives in a part of Barnstable, Massachusetts, called Centerville, where a local firefighter-training school and nearby airport contaminated the water supply for decades. The facilities allowed environmental leaks of fire-suppressing foam laden with per- and polyfluoroalkyl substances, also known as PFAS or “forever chemicals.”

Smith had been drinking the tainted water for years before he learned that it was sending his levels of certain PFAS soaring. 

...Smith sought out cholestyramine after finding publications in the scientific literature about its potential benefit for people with high PFAS exposure. Smith’s gastroenterologist was familiar with cholestyramine and considered it safe, so he agreed to give Smith a prescription.

After about 8 months of taking cholestyramine, Smith has seen his PFAS levels drop dramatically. Two fluorinated chemicals became almost undetectable in his blood, and PFHxS dropped to about 30% of what it once was. “It was definitely a psychological boost,” he says.

It's probably not a surprise that there is some kind of drug that will absorb PFAS, but I'm glad there is one that seems to be readily available.