Want to buy that super-duper ultra pure solvent for your reaction in the lab? Our mentor-by-literature, Neal Anderson, says you're out of luck, bucko (from pg. 102 of "Practical Process Research and Development"):
For initial laboratory investigations, whenever possible use solvents from bulk supplies that have been purchased for routine processing. Avoid special grades of solvents, such as HPLC-grade solvents, as processing may changes when reactions are run in bulk solvents, due to differing impurities and impurity levels.
Using a higher grade of solvent may not be necessary. [snip] Once a special grade of solvent has been shown to be necessary, the purchase of the more costly material is readily justified.Well, drat. So unless you're willing to purchase that super-duper ultra pure grade by the rail car (hopefully you'll be buying it by the rail car, anyway), you're better off with the normal stuff.