Vertex is seeking an experienced peptide chemist to join the Process Chemistry group. In this lab-based position you will be responsible for the synthesis, purification, and characterization of small organic compounds, peptides and possibly peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs). In addition, you will be responsible for any tech transfer to external CMOs for phase appropriate development and scale-up.
Key Duties and Responsibilities:
- Responsible for the synthesis, purification, and characterization of small organic compounds, peptides, and oligonucleotides under minimal supervision
- Manage relationships with external partners
- Identify and advocate for innovative synthetic strategies to project teams
Education and Experience:
PhD 6-8 years of experience, or MS degree with 9 years or experience (or equivalent education and experience) in synthetic organic chemistry or peptide chemistry Experience managing external CROs/CMOs
Experience in nucleic acid modifications and delivery of oligonucleotides are highly desirable
Experience with small- and large-scale CS-Bio solid phase peptide synthesizers (CS136x, CS936, or equivalent) in non-GMP and GMP environments
Full ad here. Best wishes to those interested.
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