- Fast-paced, eminently readable, dramatic
- A long record of Josh Boger's deepest thoughts about Vertex, a company he cares deeply about
- The inner thoughts of much of Vertex's C-suite-level executives
- Rather self-indulgent towards Vertex management's thoughts on its own culture (dude, the Garrison section?)
- The story of the manufacture of Incivek API, including the revelation that two of the five segments were manufactured by WuXi early on.
- A record of the formulation research behind Incivek, including a fairly detailed look at its spray-dried dispersion technology.
- A fantastic look behind the completely over-the-top preparations required to go in front of the FDA's advisory boards
- Towards the middle and end of the book, mostly about Invicek and Vertex's stock price and how Vertex management dealt with the ups-and-downs
- A really gripping account of one CF patient and the absolute elation/desperation that he felt with getting Kalydeco (Vertex's cystic fibrosis drug) and then not having it.
"The Antidote" is not:
- Nearly as great at telling the human stories of scientists, compared to "The Billion Dollar Molecule."
A good read, not quite as good as "The Billion Dollar Molecule", but still worth the ~$13 I paid for it.
[Two of the main protagonists of BDM, John Thomson and Mark Murcko, play a role in the story as they're now managers within Vertex's organization. There are two layoff-related episodes in the book -- I find it sadly ironic that both of these characters from the first book are intimately involved with them.]