It has been interesting for me to note how many of these people are former, not current, Big Pharma-employed. Those personally affected by layoffs at some point in their career is non-zero (20%?); I'll bet the number that have seen layoffs in their organization is basically 100%. It's a sobering reality of the economic times that we live in.
[Of course, there's probably quite a bit of sampling bias going on here; it's heavy on folks who read blogs or who are on Twitter, which is probably not representative of the overall population of working chemists.]
Also, friend of the blog Janet Stemwedel has made a good suggestion. Like any of the #ChemCoach entries? For each one you like, consider giving a $1 to the DonorsChoose Chembloggers challenge to further chemical education in K-12.
Again, if you haven't already, head over there and give it a read.