Monday, January 29, 2024

C&EN: Messer has the highest bid in auction of US government helium system

Also in this week's C&EN, this update to the goings on with the federal helium system (article by Craig Bettenhausen): 

Privatization of the US Federal Helium System limped ahead yesterday as the General Services Administration concluded its auction with only one realistic offer. The industrial gas company Messer, which currently operates the system on a contract basis, bid $353,350,000.

About 28 million m3 of federally-owned helium contained in the system was also for sale; Messer placed the only bid, offering $21 million. Helium consultant Phil Kornbluth writes in the industrial gas magazine Gasworld that the price offered for the helium itself is far below current market values. “I believe there is a good chance that it will be rejected,” he writes.

The anemic auction, which began accepting bids in July of last year, went forward despite protests and lawsuits from the industrial gas, chemical, semiconductor, medical, and aerospace industries. “The bid opening was anticlimactic, to say the least,” Kornbluth says. “But in line with my expectations.”

What I think is most interesting is this comment: 

Under the terms of the auction, the General Services Administration now has 130 days to make a decision, which could include rejecting the two bids. The agency also faces an ongoing lawsuit from Air Products. The industrial gas firm claims the sale will cause major disruptions to the US helium supply, which would violate the underlying legislation.

It is fascinating to me that no one is particularly enthusiastic (including Messer!) about the sale of this helium system. Also, I don't understand why Congress hasn't walked this back? 

Of all the historical ramifications of the 1994 Congressional election, this is definitely the one that was probably least predictable. 

C&EN: "Chemical earnings nose-dive in 2023"

In this week's C&EN, the latest comments on 2023 earnings from the major chemical companies, and it's not looking pretty... (article by Alex Tullo): 
Chemical companies’ 2023 financial results are starting to trickle in: with meek performance in Europe and China, a sluggish construction market, and industry-wide inventory destocking, it was an awful year for chemical makers. And company executives expect a turbulent start to 2024.

Dow, the first major chemical maker to report complete results, posted a 21.6% sales decline from 2022. Net income before unusual items dropped 64.9%.

Volume gains in Dow’s polyethylene and performance material and coatings businesses were more than offset by lower prices. “As we enter 2024, we expect near-term demand to remain pressured by elevated inflation, high interest rates, and geopolitical tension,” Dow chief financial officer Jeffery L. Tate said in a conference call with analysts.

BASF, the world’s largest chemical maker, had expected 2023 to be a terrible year, but the company revealed in a Jan. 19 preview that results would fall short of even its own dour expectations. Sales of $75.7 billion came in below the $79 billion–$82 billion that BASF had forecast in July. Its sales in 2022 were $94.7 billion.

Well, that's not really great news for hiring this year, but let's hope things turn around... 

Friday, January 26, 2024

Have a good weekend


This has been a fun week, and Friday is shaping up to be fun as well. I hope that you had a good week, and that you have a great weekend. See you on Monday! 

Salt in tea?

Via the New York Times, this news from friend of the blog Michelle Francl's new book: 

Can a simple cup of tea stir a dispute between two mighty countries on opposite sides of the Atlantic? Just ask the ragtag group of patriots who crudely disguised themselves and hurled chests of tea into Boston Harbor.

For a new book, an academic took a look at papers and texts covering more than 1,000 years to try to determine the best way to make a cuppa.

The conclusions of this author, Michelle Francl, a chemistry professor at Bryn Mawr College, included the expected (use tea bags only once) and the interesting (add warm milk after pouring the tea to prevent curdling).

But at least one of the recommendations was incendiary. Professor Francl advised adding a pinch of salt. Salt!

The theory is that sodium makes the tea taste less bitter.

Once again, in case you missed it: Salt. In your tea.

Professor Francl hastens to say she doesn’t dump a shakerful in every cup. The main reason to add salt is that it can rescue tea if the bag has been left too long in the water. “The sodium blocks the bitter receptors,” she said. “The tea tastes smoother and less bitter.” She advises adding just a pinch: “so little that you can’t taste the saltiness of it.”

If you read further, you'll see that a number of UK-based publications rather choked on this suggestion. I can't say I blame them for being bothered, but I think it makes a lot of sense from a chemistry perspective. I don't think I'll try it (I mostly don't drink tea enough to notice the bitter taste? And if I did, I'd think I'd just make a fresh cup. But who knows?) 

Thursday, January 25, 2024

Job posting: chemist, FDA, San Francisco, CA

Via C&EN Jobs: 

The Chemist (Advanced Analyst) serves as an analytical instrumentation specialist within the San Francisco Human and Animal Food Laboratory (SANLHAF) where they are recognized as the expert, technical authority, and resource person in this specialization. Examples of highly technical chemistry instrumentation include—but are not limited to: Inductively Coupled Plasma Mass Spectrometry (ICP-MS), or Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS).

Operates and maintains highly technical chemistry scientific equipment, same as or equivalent to the examples previously listed. Conducts studies and approved industry analytical procedures in various areas of agency concern to identify and quantify contaminants and adulterants in FDA-regulated products. May be required to troubleshoot the instrumentation such as hands-on maintenance and repair. Formulates and conducts research that evaluates new chemistry instrumentation and its applicability to the required analyses. Plans and performs the development of analytical methods in accordance with FDA needs and priorities, which requires a strong understanding of the ISO 17025 accreditation requirements as they apply to maintaining and verifying instrumentation performance. Performs verifications and validations of new chemistry methods. 

Applications will be accepted from qualified applicants. This position is being filled under an excepted hiring authority, Title 21, Section 3072 of the 21st Century Cures Act. The candidate selected for this position will serve under a career or career-conditional appointment and be paid under the provisions of the authority.  All qualified candidates should email letter of interest addressing your experience in the major duties and responsibilities of the position, detailed current resume, SF-50 (redacted for SSN and birth year, for federal employees only), and college transcript(s) (with foreign credentials evaluation, if applicable) to the ORA Executive Recruitment and Scientific Staffing Committee: ORAExecutiveandScientificRecruitment@fda.hhs.gov. Applications will be accepted through March 18, 2024. Applicants must reference: 4-Chemist-SF in the email subject line.

Full ad here. Best wishes to those interested. 

Wednesday, January 24, 2024

Who knew it was illegal to have 20% sulfuric acid in the UK?

Via Chemistry World (article by Maria Burke): 

A 29-year-old man living in Knutsford, Cheshire, has been found guilty of possessing hydrochloric and sulfuric acids without a licence. The case raises questions about the responsibilities of wholesalers selling regulated chemicals to members of the public.

Concentrated hydrochloric and sulfuric acids are regulated because they can be used in the illicit manufacture of explosives or to cause harm. In November 2018, it became a criminal offence in the UK to possess sulfuric acid above a concentration of 15% without a licence. The law was tightened to combat rising acid attacks across the country. In October last year, hydrochloric acid above 10% w/w was among several chemicals added to the list of regulated substances. Others include hexamine, phosphoric acid (above 30% w/w) and zinc phosphide.

In a raid last November, police found a ‘makeshift chemistry lab’ in the bedroom of Ashlea Henderson. According to police reports, this consisted of 21 unknown chemicals, both in and out of their containers, along with a range of equipment. As a precautionary measure the police evacuated over 100 households and called in the bomb squad. It was seven hours before residents could return to their homes.

It is interesting to me that the phenomenon of home chemists exists outside the United States (this is the first report I've seen in 10+ years.) Nevertheless, I had not idea such legal strictures existed in the UK. 

It seems to me that some enterprising small laboratory could make a bit of money by renting out a bit of space to local men who were interested in doing home chemistry, but I suspect that the legal risk would outweigh any revenue.  

Reuters: German chemical sector now hit by Red Sea Houthi conflict

Via Reuters, this news: 

FRANKFURT, Jan 22 (Reuters) - Germany's chemicals sector, Europe's largest, is starting to feel the pinch from delayed shipments via the Red Sea, becoming the latest industry to warn of supply disruptions that have forced some companies to curb production.

Crucial Asian imports to Europe ranging from car parts and engineering equipment to chemicals and toys are currently taking longer to arrive as container shippers have diverted vessels around Africa and away from the Red Sea and Suez Canal, following attacks by Yemen's Houthis.

..."My procurement department is currently working three times as hard to get something," said Martina Nighswonger, CEO and owner of Gechem GmbH & Co KG, which mixes and bottles chemicals for big industrial clients.

As a result of the delays, Gechem, which makes annual sales in the double-digit millions of euros, has lowered production of dishwasher and toilet tablets because it can't get enough trisodium citrate as well as sulfamic and citric acid.

The company is therefore reviewing its three-shift system, Nighswonger said, adding the ripple effects from the transport squeeze could remain a problem for the first half of 2024 at least. This is causing frank discussions with customers, Nighswonger added. "If we get three truck loads instead of six, each customer only gets part of their order quantity, but at least everybody gets something," she said.

Bigger speciality chemicals maker Evonik also said it was being hit by "short notice routing changes and delays", adding some ships had changed direction as many as three times within a few days.

The company said it was trying to mitigate the impact by ordering earlier and switching to air freight, which is considered a stopgap because some chemicals are not allowed to be transported by plane.

Sure wish the German chemicals sector got a better shake these days, but it sure doesn't seem like it...


Monday, January 22, 2024

C&EN: "Chemical industry should bounce ahead of the economy"

From this week's issue of Chemical and Engineering News (article by Alex Tullo): 

Economists expect the US economy to make a dreary showing in 2024, though it should manage to avoid a recession. That outlook sets a low bar for the chemical industry, and—with a challenging 2023 over—analysts predict that the sector should clear it.

The Federal Reserve and its counterparts in other countries have been raising interest rates to rein in inflation. But those moves have slowed key sectors of the economy, including new housing.

In its 2024 economic forecast, Morgan Stanley writes, “With inflation cooling, central banks around the world face a Goldilocks dilemma: If they are too easy with monetary policy, inflation could come roaring back; but if they keep policy too tight, it could trigger a recession.”

The investment bank is optimistic that policymakers will succeed. It expects US economic growth to remain positive in 2024, at 1.9%, compared with 2.4% last year. Economists’ consensus forecast is 1.0% growth for the year, Morgan Stanley says.

Goldman Sachs is also bullish. “The heaviest blows from monetary and fiscal tightening are well behind us,” the bank says in its outlook report. It puts the chance of recession at only 15%, well below economists’ consensus of 48%.

Predictions from economists at the American Chemistry Council (ACC) are more in line with the consensus. The ACC forecasts that growth will slip to 1.1% in 2024. The trade group expects housing starts—home construction is a key consumer of chemicals—to slide from an already-sluggish 1.39 million in 2023 to 1.35 million this year. It expects light-vehicle sales to be flat, at about 15.5 million units.

But against that backdrop, the ACC thinks the US chemical industry will perform better this year than it did in 2023. It forecasts a 1.5% increase in chemical output, excluding pharmaceuticals, versus the 1.0% drop in output last year.

Well, this sounds like good news to me. Here's hoping it is true. 

Friday, January 19, 2024

Have a great weekend

What a bonkers week. I don't know what the weather is like where you are, but it was not particularly pleasant for mine. At least we're not (yet) dealing with a burst pipe. I hope that you have a warm, dry abode and that you have a great weekend. See you on Monday!  

NYT: Trace elemental analysis to determine fake Kona coffee

Via the New York Times, this fascinating news about coffee farmers in Hawaii using chemistry to prevent counterfeiting of "Kona" coffee: 

...Mr. Corker said farmers had long been frustrated by the ubiquitous “Kona” beans sold by souvenir stores, coffee shops and larger retailers. They strongly suspected that the products were fake: They were far too cheap.

In 2013, a U.S. Supreme Court case caught Mr. Corker’s attention. The court found that Pom Wonderful, which sells pomegranate juice, was allowed to sue Coca-Cola for marketing a “Pomegranate Blueberry” juice that was in fact more than 99 percent apple and grape juices.

“The decision said, if you’re harmed by false labeling, you can bring a case for damages,” Mr. Corker said.

In 2019, he filed the lawsuit on behalf of Kona farmers against more than 20 companies. At the center of the complaint was a chemical analysis performed at a private lab in Salt Lake City.

James Ehleringer, a biologist at the University of Utah who ran the analysis, said that standard tests depended on the amount of water in each sample. That wouldn’t have worked on the variety of Kona products at issue.

“As you go from green beans to roasted beans, you’re changing the water content,” he said. So he borrowed an approach from geology that instead looked at the relative concentrations of rare, inorganic minerals in the beans. These ratios, he said, stay constant even at roasting temperatures.

After testing coffee samples from around the world as well as more than 150 samples from Kona farms, Dr. Ehleringer’s team identified several element ratios — strontium to zinc, for example, and barium to nickel — that distinguished Kona from non-Kona samples. “We were able to establish a fingerprint for Kona,” said Dr. Ehleringer, who described the general method in a 2020 study. “It’s the characteristics of the volcanic rock.”

Apparently Dr. Ehleringer's work hasn't been replicated by other labs, but it seems to me that the farmers of Kona coffee are incentivized to figure out and lock down what the chemical "terroir" of Kona coffee, and to harry the fakers out of business. 

Wednesday, January 17, 2024

Seville, OH chemical manufacturing facility suffers leak in 30,000 gallon tank of HCl

Via WOIO, this news: 
SEVILLE, Ohio (WOIO) - A chemical leak in Medina County prompted a shelter-in-place order Monday morning.

The Medina County Sheriff’s Office says the leak occurred at Bleachtech located at 320 Ryan Rd. in Seville. The initial shelter-in-place order was lifted around 4:30 p.m.
Here's the accompanying Ohio EPA statement
Around 10:30 a.m. a 30,000-gallon tank of hydrochloric acid at BleachTech LLC off Ryan Road in Seville began to leak due to a cracked pipe. The acid began flowing to the tank’s secondary containment unit, however that unit also has a leak. Crews are right now working to transfer the liquid from the secondary containment tank to individual storage tanks. It’s important to note that none of the material has left the property.

Right now, Ohio EPA’s on-scene coordinator is helping to facilitate efforts and crews are working to contain the leak as it is near a storm drain on property that leads to a nearby retention pond. There is currently not an immediate risk, but out of an abundance of caution, people living nearby are being asked to remain inside to avoid any potential interaction with fumes if conditions change.

That's a leak in a big tank - going to be some pretty significant preventative maintenance audits, I bet...  

Bloomberg: Global cobalt prices being pushed down by Chinese traders

Via Bloomberg: 

China’s battery industry has seized on a glut in the global cobalt market to push through a change in the way the commodity is priced.

A rapid expansion of cobalt mining in Democratic Republic of Congo and Indonesia has output racing ahead of demand, dragging down global prices. It’s also prompted a push by squeezed Chinese refineries to win changes in how cobalt is bought and sold.

Lithium and nickel also plunged along with cobalt in 2023 as supply expanded, China’s booming EV industry dialed down its breakneck pace of growth. The price slump has wreaked havoc, with new projects stalling, inventories ballooning and investor interest on the wane.

Oversupply is a particular problem for cobalt because it emerges almost entirely as a by-product of making copper or nickel. Indonesia’s booming nickel mines have already transformed the Southeast Asian nation into the world’s second-biggest cobalt producer after DRC. In the African nation, a major new source of cobalt is CMOC’s Kisanfu copper project.

So despite price volatility and a growing surplus, there’s unlikely to be any major mine shutdowns or targeted efforts to rein in cobalt production, according to Rystad Energy’s analyst Susan Zou.

“As long as the price of copper stays at decent levels, there will still be appetite for mining activity,” Zou added. “Gains in copper are still likely to offset some losses in cobalt.”

I didn't know that cobalt was a nickel mining byproduct.  

Friday, January 12, 2024

Have a great weekend!

Well, a not-quite-overwhelming, but very busy week. I hope that you are doing well, and that you have a fun weekend planned ahead of you. Who knows what my weekend will look like? I surely do not. See you on Monday! 

The case of the fake dinero

Via the New York Times, a pretty cool piece of science: 

...Now Dr. Ortega and Fabiola Bravo Hualpa, a doctoral student, believe they have shed new light on the mystery of the coin that came from nowhere. In a paper published last year in the journal Heritage Science, they described how they subjected one of the two known 1899 dineros to a barrage of scientific analyses, illuminating its possible origins and the role it might have played during an unstable era of South American history.

To the naked eye, the 1899 coin resembles other dineros: It’s silver in color and features the same coat of arms and seated woman that represents the goddess of liberty. And it’s remarkably similar in size to other dineros minted around the turn of the 20th century — about the dimensions of a U.S. dime.

But when Dr. Ortega and Ms. Bravo Hualpa bombarded the 1899 coin with X-rays and measured the light it re-emitted, they determined that the dinero was largely made of copper, zinc and nickel. This alloy is known as nickel silver. It’s commonly used to make silverware and ornamental objects and has a silvery appearance, but it contains no silver. Genuine dineros produced by the Lima Mint, on the other hand, are roughly 90 percent silver....

Has there been a novel about a post-apocalyptic world where gold and silver come back, but there is a counterfeiting problem, but one lone chemist has a XRF gun and isn't afraid to use it? 

Thursday, January 11, 2024

Job posting: Science Communications Manager, American Physical Society

Via C&EN Jobs:

Who we are: The American Physical Society (APS) is a nonprofit membership organization working to advance and diffuse the knowledge of physics through its outstanding research journals, scientific meetings, and education, outreach, advocacy, and international activities. APS represents more than 50,000 members, including physicists in academia, national laboratories, and industry in the United States and throughout the world. Position Summary:

The American Physical Society (APS) seeks an accomplished Science Communications Manager to join its strategic communications team. The Science Communications Manager will contribute to APS's mission of advancing and disseminating knowledge of physics by generating publicity for scientific research that is published in APS's journals and presented at its meetings. The ideal candidate would be a self-starter with exceptional writing, project management, and interpersonal skills. If you are passionate about science communication and possess the skills to drive APS's mission forward, please apply.

APS has a “remote first” concept that promotes equal treatment and equal access, independent of physical work location, with a majority of staff working primarily from remote work locations. This position could require in-office work and travel to attend various events and meetings as instructed by a supervisor. APS values diversity and welcomes candidates from a variety of backgrounds. 

Education:   

Bachelor’s degree in science communications, public relations, communications, journalism, or a related field.

Experience, Knowledge, Skills, and Abilities:   

Minimum of four years of related experience as a press officer at a science organization, preferably at a scientific publisher. Impeccable science writing, editing, and presentation skills. Established relationships with science journalists at top tier news outlets. Thorough knowledge of scientific research and academic publishing processes. Strategic thinker with exceptional project management and organizational skills. Strong interpersonal skills and relationship-building abilities. Proficient with communications tools like Muck Rack and Sprout Social. Experience managing social media accounts for a brand. Fluent in AP style. Background in physics is a plus.

Travel:  This position requires travel (up to 25%) to attend staff, leadership, scientific, and professional meetings and events as part of its core responsibilities. 

Full ad here. Best wishes to those interested.  

Wednesday, January 10, 2024

Interview with a senior Novo Nordisk scientist

Fascinating and very... European interview in Der Spiegel with the inventor of liraglutide, Lotte Bjerre Knudsen: 

DER SPIEGEL: We have a different supposition: Novo Nordisk grew up with insulin, which will now be used less in the fight against diabetes. And your company didn’t want to give up its old revenue generator.

Knudsen: I’m not buying that. Why didn’t Merck, Bristol-Myers Squibb, Pfizer and all the other manufacturers prioritize anti-obesity drugs?

DER SPIEGEL: But you had to struggle against resistance within the company.

Knudsen: It’s true that over the years I’ve clashed with some colleagues who focus on insulin. People told me directly that they thought the GLP-1 peptide was a bad idea. We wouldn’t need new injectors for diabetes or obesity. Even our former CEO jokes today that he didn’t believe in a successful anti-obesity drug. But I was allowed to continue researching.

I'm genuinely very impressed with people who worked on a hard problem for many years and have had it shown fruit. I suspect that all of us have these moments, but it's always very cool when their passions turn out to be very, very successful. Congratulations to her, and best wishes to all of us in our individual endeavors. 

Tuesday, January 9, 2024

The 2024 Chemistry Faculty Jobs List: 497 research/teaching positions and 69 teaching positions

The 2024 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 497 research/teaching positions and 69 teaching positions

Want to help out? Here's a Google Form to enter positions.

To see trending, go to Andrew Spaeth's visualization of previous years' list.

On January 10, 2023, the 2023 Chemistry Faculty Jobs List had 568 research/teaching positions and 558teaching-focused position.

Want to talk anonymously? Have an update on the status of a job search? Here's the first open thread. Here's a link to the second, open thread. Here's a link to the current, third open thread. 

Don't forget to click on "load more" below the comment box for the full thread. 

Job posting: Senior Laboratory Instructor, Chemistry Department, Colgate University, Hamilton, NY

From the inbox: 

The Chemistry Department at Colgate University invites applications for a full-time senior laboratory instructor position beginning fall semester 2024. A PhD in chemistry or a closely related field is required at the time of hire or shortly after. The successful candidate will teach instructional labs for organic and general chemistry. 

Consistent with the candidate’s expertise, demonstration of effective teaching, and the needs of the department, there may also be opportunities to teach lecture components of introductory and foundational level chemistry courses, as well as courses in Colgate’s Liberal Arts Core Curriculum. The successful candidate may assist with the preparation of materials for instructional labs, and collaborate with our lab coordinators and other faculty to develop laboratory manuals and new experiments. 

A cover letter, curriculum vitae, a statement of teaching interests, a diversity statement, and three letters of recommendation must be submitted through http://apply.interfolio.com/138362. 

Full ad here. Best wishes to those interested. 

The Chemical Engineering Faculty Jobs List: 130 positions

The Chemical Engineering Faculty Jobs List has 130 positions. Find an error or have a question? Find an error? Contact @Heatherlec620 or @G_sribala. 

This is the link to the open thread. 

Monday, January 8, 2024

C&EN: "Can Kenya become a direct-air-capture hub?"

Fascinating story about a Kenya-based startup in this week's C&EN (article by by Geoffrey Kamadi):  

Octavia Carbon, a Kenya-based start-up, has an audacious goal. It wants to become the first company to deploy direct-air-capture (DAC) technology—a method of removing carbon dioxide from the atmosphere—outside the US and Europe.

The hurdles are high. The technology is new and is being used commercially at only two sites in the world. And Octavia needs more R&D before it can advance its process from pilot to commercial scale. Moreover, the technological infrastructure in Kenya is less robust than that of higher-income countries, to say nothing of the financial infrastructure needed to service a DAC venture.

But Martin Freimüller, Octavia’s CEO and founder, says he’s confident the firm will overcome the infrastructure constraints. He’s counting on Kenya to deliver three unique attributes: abundant renewable energy, a local geology that is well suited to the project, and a talented human resource pool that makes the country a competitive place for developing DAC...

...Freimüller’s stay in Kenya has convinced him that the country has the right attributes to develop a DAC project.

Top on Freimüller’s list is Kenya’s abundant renewable energy resources, which are the source of over 90% of the country’s energy. The country is the leading geothermal power producer in Africa and the seventh largest in the world, but it uses only about 10% of its power capacity. The amount going untapped, Freimüller says, is enough to power Octavia’s DAC plants to mega–metric ton scale.

I don't claim to have any climate change answers, but worthwhile to know that people in Kenya are thinking about local potential solutions. It will be interesting to see if these solid amine sorbents end up succeeeding. 

No, no, that's not how this works

Also in this week's C&EN, this letter to the editor: 

One topic never mentioned in the article on Kristie Koski was how many graduate students have successfully completed their PhD with Koski, either at Brown University or at the University of California, Davis (C&EN, Oct. 30, 2023, page 17). Her website doesn’t mention the names of current or former graduate students or postdoctoral scholars. Her mentoring skills should be a major factor in considering tenure.

I am baffled by her own description of herself on her website, which reads in part, “Professor Koski is an adrenaline junky known for epic adventures: climbing big walls, surfing 30 foot waves, destroying expensive kayaks, and driving her over-powered muscle car way too fast.” No mention of her love of teaching and mentoring new scientists.

An interview with current graduate students might help give a better perspective on professor Koski and whether she is ready for tenure.

Many scientists who get awards and grants do not make good professors.

Roseann Csencsits

Pleasanton, California

I stipulate Dr. Csencsits' point about the disconnect between well-regarded academic researchers and their teaching prowess, but I don't think that "mentoring skills" have ever been a major factor in the granting of tenure, especially at large research universities like UC-Davis. Productivity, productivity, productivity seem to be the top three factors, with collegiality within professors as a trailing consideration. 

Friday, January 5, 2024

Have a great weekend!

Well, the year started out fast. I hope that you had a more peaceful week than I did, and that you have a great weekend. See you on Monday! 

Thursday, January 4, 2024

C&EN: "Chemours helps end counterfeiting ring"

Via Chemical and Engineering News (article by Alex Tullo): 
Chinese authorities, with the help of local Chemours affiliates, have shut down a large-scale operation that was making a counterfeit version of Chemours’s Viton FreeFlow fluoroelastomer. Officials found 4.7 metric tons of the fake product and a large quantity of precursors. The operation also possessed forged packaging materials and business documents, as well as some genuine Viton. “Counterfeit goods, especially in the chemical sector, pose substantial risks to safety, product quality, and the reputation of authentic products,” says Eric von Brockdorff, global product and business director for Chemours.

I'm curious to know why the Chinese government will help with some counterfeiting and not others?  

Wednesday, January 3, 2024

Update to the Koski story

Via C&EN (article by Sam Lemonick), an update to the Kristie Koski saga: 

The University of California, Davis, has granted tenure to physical chemist Kristie Koski. The decision ends one chapter of a 4-year saga of punishments, lawsuits, and recriminations that Koski has said is exacting a toll professionally and emotionally.

Koski, who joined the faculty at UC Davis in 2013, submitted her original tenure application in 2019. Her review process included a number of irregularities. The chair of her department, with whom Koski had had prior disagreements, produced a letter of censure against Koski during the chemistry faculty’s vote on her candidacy. It accused her of bullying or intimidating two trainees.

One trainee had not followed all the check-out steps when he left her lab for another job. Koski had voiced concerns to her chair that the other may have sexually harassed undergraduates he worked with. Koski was later cleared of any wrongdoing in the latter case...

I dunno what to say, other than that "academia is sometimes very weird." Glad it seems to have finally worked out for Professor Koski. 

Tuesday, January 2, 2024

The 2024 Chemistry Faculty Jobs List: 491 research/teaching positions and 64 teaching positions

The 2024 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 491 research/teaching positions and 66 teaching positions

Want to help out? Here's a Google Form to enter positions.

To see trending, go to Andrew Spaeth's visualization of previous years' list.

On January 3, 2023, the 2023 Chemistry Faculty Jobs List had 567 research/teaching positions and 55 teaching-focused position.

Want to talk anonymously? Have an update on the status of a job search? Here's the first open thread. Here's a link to the second, open thread. Here's a link to the current, third open thread. 

Don't forget to click on "load more" below the comment box for the full thread. 

Job posting: Senior Laboratory Instructor, Chemistry Department, Colgate University, Hamilton, NY

From the inbox: 

The Chemistry Department at Colgate University invites applications for a full-time senior laboratory instructor position beginning fall semester 2024. A PhD in chemistry or a closely related field is required at the time of hire or shortly after. The successful candidate will teach instructional labs for organic and general chemistry. 

Consistent with the candidate’s expertise, demonstration of effective teaching, and the needs of the department, there may also be opportunities to teach lecture components of introductory and foundational level chemistry courses, as well as courses in Colgate’s Liberal Arts Core Curriculum. The successful candidate may assist with the preparation of materials for instructional labs, and collaborate with our lab coordinators and other faculty to develop laboratory manuals and new experiments. 

A cover letter, curriculum vitae, a statement of teaching interests, a diversity statement, and three letters of recommendation must be submitted through http://apply.interfolio.com/138362. 

Full ad here. Best wishes to those interested. 

The Chemical Engineering Faculty Jobs List: 130 positions

The Chemical Engineering Faculty Jobs List has 130 positions. Find an error or have a question? Find an error? Contact @Heatherlec620 or @G_sribala. 

This is the link to the open thread. 

Tuesday, December 26, 2023

The 2024 Chemistry Faculty Jobs List: 490 research/teaching positions and 64 teaching positions

The 2024 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 490 research/teaching positions and 64 teaching positions

Want to help out? Here's a Google Form to enter positions.

To see trending, go to Andrew Spaeth's visualization of previous years' list.

On January 3, 2023, the 2023 Chemistry Faculty Jobs List had 567 research/teaching positions and 55 teaching-focused position.

Want to talk anonymously? Have an update on the status of a job search? Here's the first open thread. Here's a link to the second, open thread. Here's a link to the current, third open thread. 

Don't forget to click on "load more" below the comment box for the full thread. 

Job posting: Senior Laboratory Instructor, Chemistry Department, Colgate University, Hamilton, NY

From the inbox: 

The Chemistry Department at Colgate University invites applications for a full-time senior laboratory instructor position beginning fall semester 2024. A PhD in chemistry or a closely related field is required at the time of hire or shortly after. The successful candidate will teach instructional labs for organic and general chemistry. 

Consistent with the candidate’s expertise, demonstration of effective teaching, and the needs of the department, there may also be opportunities to teach lecture components of introductory and foundational level chemistry courses, as well as courses in Colgate’s Liberal Arts Core Curriculum. The successful candidate may assist with the preparation of materials for instructional labs, and collaborate with our lab coordinators and other faculty to develop laboratory manuals and new experiments. 

A cover letter, curriculum vitae, a statement of teaching interests, a diversity statement, and three letters of recommendation must be submitted through http://apply.interfolio.com/138362. 

Full ad here. Best wishes to those interested. 

Friday, December 22, 2023

Have a great weekend

This week wasn't as quiet as I hoped, but it had its quiet moments. Here's hoping that you had a good week, and that you have a wonderful, restful weekend. See you (briefly) on Monday. 

FDA: "FDA warns consumers not to use counterfeit Ozempic (semaglutide) found in U.S. drug supply chain"

 Via FDA's website: 

FDA continues to investigate counterfeit Ozempic (semaglutide) injection 1 milligram (mg) in the legitimate U.S. drug supply chain and has seized thousands of units of the product. The agency advises wholesalers, retail pharmacies, health care practitioners and patients to check the product they have received and not distribute, use, or sell products labeled with lot number NAR0074 and serial number 430834149057 as pictured below. Some counterfeit products may still be available for purchase.

FDA and Novo Nordisk (manufacturer of Ozempic) are testing the seized products and do not yet have information about the drugs’ identity, quality, or safety.

Additionally, analysis found the needles from the samples are counterfeit. Accordingly, the sterility of the needles cannot be confirmed, which presents an increased risk of infection for patients who use the counterfeit products. Based on analyses completed to date, other confirmed counterfeit components within the seized products are the pen label, accompanying health care professional and patient information, and carton. 

FDA is aware of five adverse events from this lot, none of which are serious and are consistent with known common adverse reactions to authentic Ozempic, which are nausea, vomiting, diarrhea, abdominal pain and constipation.

It seems to me that this sort of thing is to be expected with such a revolutionary drug. It seems to me that the only thing that Novo could have done was to ensure a plentiful supply of Ozempic from the start, but I'm not sure there was enough fill-and-finish capacity available, especially with them surely competing with every vaccine manufacturer for available lines... 

Thursday, December 21, 2023

Job posting: Staff scientist, Synthesis and Development, Innophos, Cranbury, NJ

From the inbox: 

Innophos is seeking a Staff Scientist for the Synthesis and Development Lab based in our Cranbury, NJ location. The successful candidate will perform lab-based experiments and testing to support new product development in the phosphate and nutrition business and provide technical support to manufacturing sites across the company.

Key Responsibilities

  • Design and execute experiments and procedures to prepare materials/formulations in the R&D lab
  • Perform hand-on benchtop synthesis and evaluation of Innophos and customer materials
  • Record all relevant information related to product development, sample characterization & experimental design
  • Apply product and application know how to identify optimum technology solutions
  • Conduct general research on targeted industries/topics, including scientific search and reading and evaluating published literature
  • Lead and drive to completion of NPD projects through SPARC (Stage-Gate) process
  • Present data generated to project and management teams
  • Comply with all safety policies, practices, and procedures

Required Education and Experience

  • B.A. with 5+ years of experience preferred in specialty chemical industry, or M.S. degree with 3+ years of experience, or PhD. degree
  • Areas of study: Chemistry, Materials Science, or related field
  • At least 3 or more years of experience working in a chemistry/materials science lab, experience of material synthesis especially inorganic materials is strongly preferred 
Full ad here. Best wishes to those interested. 

Wednesday, December 20, 2023

A Christmas letter for your family

A Chemjobber Christmas tradition, updated for 2023. Send a PDF to your family - try it, it works! 

December 20, 2023

Dear family member:

This holiday season, your relative is in his or her fifth/sixth/seventh/_______ year of graduate school in chemistry. This is a delicate time in your students’ lives -- please make interactions smooth for all by following these simple suggestions:

  1. Please supply lots of fresh fruit and vegetables -- they are in short supply. 

  2. Do not offer pizza, which is an all-too-common part of their diets. 

  3. Sleep is a rare commodity in graduate school; please turn down sheets and fluff pillows. Be prepared to see them about 24 hours after they get home.

In attempting to communicate with your graduate student, please avoid asking the following questions: 


  1. When are you going to finish? 

  2. What can you do with your degree? 

  3. Will you be the kind of doctor that helps people? 

  4. Can you make Ozempic? I heard there’s a shortage. 

  5. There's a clinical chemistry department at my hospital -- can you get a job there? 

  6. Why do you need a postdoc? Haven't you gone to enough school? 

  7. Did I hear your paper was on PubPeer?

  8. MEGABIOGENE has opened a facility nearby -- can you get a job there?  

  9. How about a startup? I hear AI is still hot. 

  10. I see [insert high school rival here] has finished medical school -- how much will they be
    making? 

  11. Have you thought about teaching? I heard professors have a stable job. 

  12. When are you going to finish? 


In following these simple suggestions, I trust that you, your graduate student and your family will have a very Merry Christmas and a Happy New Year.

Very sincerely,

Chemjobber

Tuesday, December 19, 2023

The 2024 Chemistry Faculty Jobs List: 481 research/teaching positions and 60 teaching positions

The 2024 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 481 research/teaching positions and 60 teaching positions

Want to help out? Here's a Google Form to enter positions.

To see trending, go to Andrew Spaeth's visualization of previous years' list.

On December 20, 2022, the 2023 Chemistry Faculty Jobs List had 564 research/teaching positions and 48 teaching-focused position.

Want to talk anonymously? Have an update on the status of a job search? Here's the first open thread. Here's a link to the current, second, open thread. This will be the third open thread when I close the second thread shortly. 

Don't forget to click on "load more" below the comment box for the full thread. 

The Chemical Engineering Faculty Jobs List: 130 positions

The Chemical Engineering Faculty Jobs List has 130 positions. Find an error or have a question? Find an error? Contact @Heatherlec620 or @G_sribala. 

This is the link to the open thread. 

Monday, December 18, 2023

C&EN: "Ukraine’s research capacity is down 20% due to war"

Via Chemical and Engineering News (article by Krystal Vasquez):

Nearly one in five Ukrainian scientists have left the country since Russia’s invasion began in February 2022, according to a new study that surveyed over 2,500 researchers who’ve been affected by the war (Humanit. Soc. Sci. Commun. 2023, DOI: 10.1057/s41599-023-02346-x) . Of the scientists who stayed in Ukraine, 40% are devoting less time to research than they did before the war, and around 10% have stopped conducting research entirely.

Altogether, Ukraine’s research capacity is down 20%, and this loss will greatly impact the country for years to come. “Science and innovation fuel long-term economic growth,” says Gaétan de Rassenfosse, an economist at the École Polytechnique Fédérale de Lausanne and one of the authors of the study. “The extent that we destroy the science system today compromises the long-term growth opportunity of the country tomorrow.”

And the situation may not improve even if the war ends, de Rassenfosse explains. If the war suddenly stopped today, around 7% of Ukraine’s scientists would have permanently left research, the researchers estimate. Their absence could sap teachers and mentors for the country’s science students.

The international community has been providing support to Ukrainian scientists, but more can be done, the researchers say. For example, institutions could offer longer-term contracts to those who left Ukraine, since at the time of the survey, only 14% of these migrant scientists had secured a long-term contract abroad.

I am not familiar with the scholarship of refugee migration, but I wonder if there has ever been such an immediate impact on pharmaceutical research (I imagine World War II had such moments). 

Friday, December 15, 2023

Have a great weekend

Gosh, this has been a bonkers week, but here we are. I hope that you've had a great week, and I hope you have a great weekend. See you on Monday. 

Hydrogen cyanide found on Saturn moon

Via the New York Times: 

Scientists have detected a poison among the spray of molecules emanating from a small moon of Saturn. That adds to existing intrigue about the possibility of life there.

The poison is hydrogen cyanide, a colorless gas that is deadly to many Earth creatures. But it could have played a key role in chemical reactions that created the ingredients that set the stage for the advent of life.

“It’s the starting point for most theories on the origin of life,” said Jonah Peter, a biophysics graduate student at Harvard. “It’s sort of the Swiss Army knife of prebiotic chemistry.”

Thus, Mr. Peter was excited when he found hydrogen cyanide at Enceladus, an icy moon of Saturn that is about 310 miles across. It has a subsurface ocean that makes it among the most promising places to look for life elsewhere in the solar system.

If you read further in the article, they've found acetylene and propene too. I suppose that's not thaaaat surprising, but it's still pretty cool nonetheless. 

(You could imagine, if energy was limitless, that you could use the atmosphere in order to get your petrochemical-type molecules for making stuff for space explorers...) 

Thursday, December 14, 2023

Job posting: Executive Director – Head of Process Chemistry, Alberta Site, Gilead

From the inbox: 
KEY RESPONSIBILITIES

The Executive Director – Head of Process Chemistry, Alberta Site reports to Gilead’s Global Head of Technical Development and is responsible for leading a team of 75 scientists to develop safe, robust, and cost-effective processes for the manufacture of clinical and commercial synthetic molecule Drug Substances.  In addition, the Executive Director will be a key member of the Alberta Site Leadership team, supporting operations, quality and manufacturing process plans that ensure the reliable production and delivery of high-quality drug substance products. They will also lead, model, and create an environment of inclusion, develop talent, and empower teams to achieve their goals.

The successful candidate will contribute their technical expertise and functional knowledge with industry know-how across multiple sites and multiple teams, directs execution of scientific research and development strategies and plans that support and align with organizational and therapeutic area strategic direction and roadmap to enable corporate objectives and ambitions. 

JOB DESCRIPTION
  • Lead and drive line function to collaborate across multiple sites and CMC functions to support and progress the small molecule portfolio advancement. Ensure collaboration across relevant Technical Development and Pharmaceutical Development and Manufacturing (PDM) functions (i.e., Process Chemistry in Foster City, Analytical Development, Formulation Development).
  • Lead teams with accountability to investigate a wide variety of engineering and scientific principles and concepts to potential inventions, drug development through to commercialization, and leadership to conceive and develop critical, long-range solutions.
Full ad here. Best wishes to those interested. 

Tuesday, December 12, 2023

Monday, December 11, 2023

C&EN: "UK scientists fear impact of new immigration rules"

In this week's C&EN, this news (article by by Benjamin Plackett) 

In a bid to cut immigration, the British government says it will raise the minimum salary that skilled migrants must earn to qualify for a work visa to £38,000 ($47,800) from £26,200 ($33,000). The governing Conservative party is keen to make ground on promises to stem rising rates of immigration ahead of a general election, due to take place in 2024.

The new rules mean that about 300,000 people who came to the UK last year would now be ineligible to do so, according to the government’s calculations. Many scientists are concerned because the new threshold is higher than the salary of most early-career researchers.

“We’ll see still fewer overseas applicants for postdocs in the UK,” says Ben Sheldon, a zoologist at the University of Oxford. “We don’t train enough high-quality PhD students to be able to recruit entirely from within.” More than 60% of postdoctoral researchers in the UK come from overseas, according to a report from the Royal Society, the UK’s scientific academy.

This anxiety is echoed by others. “These proposed changes, combined with big increases in visa costs earlier this year, run the risk that the UK becomes a less and less attractive destination for the world’s brightest and best talent,” says Daniel Rathbone, interim executive director of the Campaign for Science and Engineering (CaSE), which lobbies for better science funding in the UK.

I can't pretend like I understand UK immigration policy, but it seems to me that raising a salary threshold by 45% in a year will cause large disruptions. I wonder if this will get walked back? 

Chemistry students in Georgia in accident; PPE prevented major injuries

Via the Marietta Daily Journal: 

Two female Marietta High School students received chemical burns due to an accident in a chemistry lab Thursday afternoon, Principal Marvin Crumbs announced in a message to families.

Around 4:30 p.m. Thursday, Marietta Superintendent Grant Rivera told the MDJ that both students were in the process of being discharged from a local hospital.

The students, who Rivera said were upperclassmen, were burned when a “routine lab experiment” using sulfuric acid and magnesium went awry.

“Based on feedback from the teacher, the concentration of the sulfuric acid may have been too high, because the reaction occurred quicker and more abruptly than expected,” Rivera said. “As a result, the acid splattered and got on both the student conducting the experiment, as well as … a child in the lab at a table nearby.”

Students were wearing the required safety gear including aprons and goggles, Rivera said, and under the direct supervision of a teacher.

Following the accident, all safety protocols were followed, Rivera said, including placing the injured students underneath an emergency shower in the lab, followed by an immediate response from administrators and emergency services personnel.

“Obviously, upon reflection … we recognize that we have to have greater caution around higher concentrations of chemicals,” Rivera said. “So we will meet with the teacher, meet with the science department, to determine, as we would with any situation, 'What do we need to learn from this?' … We train for it, but it's highly unusual, and obviously we do not want it to happen again.”

I've done this experiment - guessing that someone added something a bit too quick. Nice to see that the students had PPE on. 

Friday, December 8, 2023

Have a good weekend

This has been kind of a bonkers week, but that's all right. Almost all the way through it, and Friday looks to be (kind of) relaxing for me. I hope you had a good week, have a great weekend, and I'll see you on Monday. 

C&EN: "Nick Ishmael-Perkins will be the next editor in chief of C&EN"

From C&EN's Krystal Vasquez: 

Nick Ishmael-Perkins will be the next editor in chief of C&EN. Ishmael-Perkins is currently a senior consultant for the International Science Council and will move to the magazine in February 2024.

In his current position, Ishmael-Perkins focuses mostly on improving the public’s perception of science. For example, he helped produce an award-winning multimedia series that explores how to better communicate scientific discoveries. Earlier in his career, Ishmael-Perkins served as the director of SciDev.Net, an online news outlet that covers how science and technology can aid in global development. He has also worked as a journalist, media trainer, and project manager in sub-Saharan Africa and South Asia.

“We are proud to have a talented individual like Nick joining” the American Chemical Society, ACS CEO Albert G. Horvath says in a statement. “We’re excited about the vision, energy, leadership and expertise he brings to C&EN.” C&EN is published by ACS but is editorially independent.

I look forward to Ishmael-Perkins' leading of C&EN, and I hope that this is the beginning of a long and peaceful time for C&EN's staff, which has been through it for the past few years. 

Thursday, December 7, 2023

Job posting: Biotech Intellectual Property Patent Agent/Technical Specialist (NY/CA)

Via C&EN Jobs: 
Duane Morris seeks a biotech patent prosecution, opinion and counseling patent agent/technical specialist (Ph.D.) with 0-5 years of experience, for its San Diego or New York office. The successful candidate will hold an advanced degree (i.e., Ph.D.), from an accredited institution, in biochemistry, immunology, molecular biology or microbiology, and have experience practicing before the USPTO that is commensurate with the candidate’s years in practice. Additional appreciation of organic chemistry, and bioinformatics is desired. Candidate must be admitted (or have the ability to become admitted) to practice before the USPTO as a registered U.S. Patent Agent.

The target annual pay range for this role in San Diego is $140,000-$160,000. Actual pay will vary depending upon various factors, including relevant experience, skill-set, current business needs and market factors. The compensation range listed is just one component of Duane Morris' total comp package for employees, which, depending on the position, may also include discretionary bonuses and incentive packages, and firm-sponsored benefit programs.

The target annual pay range for this role in New York is $150,000-$170,000. Actual pay will vary depending upon various factors, including relevant experience, skill-set, current business needs and market factors. The compensation range listed is just one component of Duane Morris' total comp package for employees, which, depending on the position, may also include discretionary bonuses and incentive packages, and firm-sponsored benefit programs.

Full ad here. Best wishes to those interested.  

Wednesday, December 6, 2023

Dan Baldassarre is lying about my friends

I’m never surprised to read complaints about the teaching and learning of organic chemistry on Twitter. It is an evergreen topic to the point that I used to be amused about the complaints, and then I was offended by them and now I am merely saddened. 

However, this post on (the former) Twitter by Dan Baldassarre was a new low, because Professor Baldassarre is a current professor, and not simply a random medical student or recently graduated physician. 

Continually flabbergasted by organic chemistry professors who don't interrogate their course design despite half the students failing. The callous, inflexible, sink-or-swim culture around this course is so gross. If half your students regularly fail, you're not doing your job.

He had the unfortunate circumstance of having his tweet become quite popular. He doubled down with this: 

O chem profs getting together to celebrate failing half their students and preserving the holy sanctity of med school 

The accompanying gif is that of some odd folks dancing wildly. On being asked about it by Debbie Gale Mitchell (a friend, and a teaching professor of chemistry), he had this reply: 

I’m not referring to any one person, merely to the preponderance of such professors across the field. As evidenced by the replies and quotes, they are quite common. I don’t doubt there are systemic issues at play as well though.

There are three factual claims here: 

  1. The failure rate for organic chemistry students is 50% 
  2. Professors have created a “callous, inflexible, sink-or-swim culture” and are celebrating the failure of their students, and are directly or indirectly attempting to preserve med student quality. 
  3. Organic chemistry professors who celebrate the failure of such students are a “preponderance”, that is, a majority of organic professors are happy to see their students fail. 

What I like about Baldassarre claim 1 is that it’s immediately falsifiable. What I learned is that there is not a lot of data out there. A brief informal survey indicates that current DFW rates among professors is well below 30%; a cursory look at the chemical education literature indicates that rates at 50% are indeed documented (as far back as 1999, and as recently as 2008.). I have a strong sense that the recent rates at Professor Baldassarre’s own institution are not nearly so high - I wonder if he has investigated? Nevertheless, the data is equivocal. 

What I am much more bothered by is Professor Baldassarre’s second claim - that organic professors are genuinely happy to fail students, and this position is held by most organic professors. I count A LOT of organic chemistry professors as my friends. Over the years, I’ve seen that they genuinely want their students to learn, and care about their students learning the material. I have heard none of the hundreds of organic professors I’ve talked to over the years celebrate the failure of their students; rather, I hear these professors doing their best (contra Baldassarre) to learn, to care, to listen and meet their students where they are. What is even more specious about his tweet is that chemistry professors care a whit about medical school admissions. Rather, I have found organic professors to view the MCAT as a burden to be shouldered, when they have talked about it at all. 

It’s true, I'm biased. I was, for something like 20 years, a professional organic chemist, and even now, I work in industrial organic chemistry. I genuinely love my field. It's the chemistry of life and I think organic chemistry is the perfect synthesis of science and craft and art. I know that professional organic chemistry educators try to communicate that same love to their students, even the pre-meds. Organic chemistry education could always be better - but that’s not Dan Baldassarre’s claim. Rather, his claim is that my organic professor friends are uncaring sadists. He’s wrong, and I wish that he would stop lying about my friends.

Tuesday, December 5, 2023

The 2024 Chemistry Faculty Jobs List: 472 research/teaching positions and 49 teaching positions

The 2024 Chemistry Faculty Jobs List (curated by Andrew Spaeth and myself) has 472 research/teaching positions and 49 teaching positions

Want to help out? Here's a Google Form to enter positions.

To see trending, go to Andrew Spaeth's visualization of previous years' list.

On December 6, 2022, the 2023 Chemistry Faculty Jobs List had 530 research/teaching positions and 35 teaching-focused position.

Want to talk anonymously? Have an update on the status of a job search? Here's the first open thread. Here's a link to the current, second, open thread. 

Don't forget to click on "load more" below the comment box for the full thread. 

Job posting: NMR facility coordinator, Department of Chemistry, University of New Mexico, Albuquerque, NM

From the inbox: 

Under general supervision, employs a broad knowledge of principles, practices, and procedures in a particular field of specialization to plan, coordinate, and conduct research.

  • Coordinates all activities in Nuclear Magnetic Resonance (NMR) facility, includes nitrogen and helium fills, billing, and maintenance of NMR instruments.
  • Lead, guide, and train staff/student employees, interns, and/or volunteers performing related work; may participate in the recruitment of volunteers, as appropriate to the area of operation of NMR instruments
  • Maintain and expand user list of NMR facility within and outside of UNM.
  • Plans, coordinates, and conducts scientific research requiring judgment in the independent evaluation, selection, and substantial adaptation and modification of standard scientific techniques related to NMR
  • Applies an analytical approach to the solution of a wide variety of problems or applies specialized techniques or ingenuity in selecting and evaluating approaches to unforeseen or novel problems related to NMR.
  • Demonstrates and applies thorough understanding of scientific methods, research protocols, assessment instruments, and data interpretation.
MS preferred. Full ad here. Best wishes to those interested. 

The Chemical Engineering Faculty Jobs List: 123 positions

The Chemical Engineering Faculty Jobs List has 123 positions. Find an error or have a question? Find an error? Contact @Heatherlec620 or @G_sribala. 

This is the link to the open thread. 

Monday, December 4, 2023

C&EN: Whither older NMRs

Great article by Celia Henry Arnaud in this week's C&EN about Varian NMRs, including this bit of speculation: 
While researchers deal with the practical ramifications of Agilent’s exit, WUSTL’s Hayes is considering the broader implications. “I think we might see changes, because what this has shown is that it’s like a single-point-of-failure model. We are now in a situation where hardware with very high capital equipment costs is purchased, only to learn that the company may choose not to be in this business within a year or two thereafter,” she says.

NMR instruments are unique in their longevity, Hayes notes. “In many cases we have been fortunate as a department to keep them for 20 or 30 years. So what do you do in terms of robust decision-making when the landscape for vendors of such equipment is so uncertain?”

Hayes predicts that in the next decade or two there could be a shift toward benchtop instruments for routine analysis in synthesis labs—both to avoid the large purchases and to circumvent difficulties with the helium market. But until then, she adds, “every research-oriented chemistry department needs an NMR—at least one, if not two.”

Is anyone actively moving towards benchtop NMRs in synthetic chemistry? I'd love to know if this is happening... 

C&EN: "Novo Nordisk to expand GLP-1 production in France"

In this week's C&EN, this news (article by Rick Mullin): 
Novo Nordisk will invest $2.3 billion to expand manufacturing at its plant in Chartres, France. The project includes finished-drug production for products based on a glucagon-like peptide-1 (GLP-1) agonist, semaglutide, the active ingredient in two of its blockbusters. Last month, the company announced a $6 billion expansion at its plant in Kalundborg, Denmark, which makes GLP-1 products. Novo Nordisk has been straining to keep up with demand for semaglutide. Its Weygovy, a weight loss drug, and Ozempic, for type 2 diabetes, booked sales of $4.5 billion in the third quarter, a 37% increase over the same period last year.

It will be fascinating to see the ripples of Wegovy/Ozempic through the industry... 

Friday, December 1, 2023

Have a great weekend


Well, this has been a bonkers week, but I'm almost through it. I hope that you had a calmer week than I did, and that you have a wonderful weekend. I am looking forward to spending it with my family. See you on Monday!

C&EN: ACC predicts a sluggish 2024

Via C&EN's Alex Tullo, this grim news:

The US chemical industry had a tough 2023, and next year it will have to weather a tougher economic climate, possibly even a downturn.

That was the message delivered by the American Chemistry Council, a chemical industry trade group, in its industry forecast on Nov. 28. The ACC estimates that the industry’s output, excluding pharmaceuticals, will decline by 1.0% in 2023. It predicts a modest turnaround to 1.5% growth next year.

“We saw weakness really emerge last year in the third quarter, and it’s continued through much of this year,” ACC chief economist Martha Gilchrist Moore told reporters on a conference call.

...For example, Moore pointed out, student loan repayments are starting up again, credit card debt defaults are increasing, and consumers have worked through much of the savings they accumulated during the pandemic.

After posting 2.3% growth in gross domestic product in 2023, the US will experience economic growth of only 1.1% in 2024, the ACC expects.

There is this weird aspect of the economy these days, where there is a lot of negative data from standard economic indicators, and yet it does not yet seem to have shown up in the unemployment numbers (which, I imagine, are a lagging and not a leading indicator.) I do not wish it to be so (for many reasons) but I am concerned that 2024 will be a worse hiring year for industrially-oriented chemists than 2023, but I don't really have a great sense of this.