April 2009 Sanofi overhauls its pipeline, ending development of more than a dozen drugs and vaccines, including an antidepressant. The following year, the company cuts hundreds of sales jobs, citing its reduced activities in central nervous system (CNS) research.
January 2010 GlaxoSmithKline ends neuroscience drug R&D in Harlow, England, and abandons some areas of neuroscience research, including depression and pain.
July 2010 A year after its acquisition of Schering-Plough, Merck & Co. closes a neuroscience research lab in the U.K. and consolidates activities at two sites in the U.S.
December 2011 Novartis announces the closure of its neuroscience R&D site in Basel, Switzerland, and the formation of a smaller group in Cambridge, Mass., to study the genetics of certain CNS disorders.
February 2012 AstraZeneca announces it will lay off some 2,200 scientists, mostly in neuroscience R&D. The firm is closing a research lab in Montreal and ending R&D in Södertälje, Sweden.Wow. That's not really good news for anyone, either scientists or patients. I hope this is rock bottom, to borrow a phrase.