The edX course (Medicinal Chemistry) starts October 13th and runs eight weeks.
Cost: free with both free and for-pay certification options
Prerequisites: general chemistry (binding energies, intermolecular forces), some organic chemistry (line-angle structures and functional groups), knowledge of cell parts and functions, comfort with logarithmic and exponential equations
Time required: 1 hour of video per week, completing all assignments will require approx. 1 hour per day
Topics (approx. 1 wk each)
(1) drug approval process (early drugs, clinical trials, IP factors)
(2) enzymes and receptors (inhibition, Ki, types of ligands, Kd)
(3) pharmacokinetics (Vd, CL, compartment models)
(4) metabolism (phase I and II, genetic factors, prodrugs)
(5) molecular diversity (drug space, combi chem, libraries)
(6) lead discovery (screening, filtering hits)
(7) lead optimization (FG replacements, isosteres, peptidomimetics)
(8) important drug classes (selected examples)
Target audience: anyone with an interest in the structural basis of how drugs are designed.Sounds like an interesting class!