The need for solvent exchanges in the sense of displacing one solvent by another without passing through a liquid free state practically does not exist outside of process chemistry. At laboratory scale, when one solvent needs to be replaced with another, the solution contents are placed in a r.b. flask, set spinning on the vacuum rotary evaporator with appropriate heating and strong condensing efficiency. When the first solvent has been completely evaporated then the required new solvent is added and the solutes brought back into solution by swirling and scraping.
On scale, evaporation to dryness is not possible without caking and possibly charring. Even if it were possible to avoid degradation, the layer of non-volatile residue would become so thick on the reactor's wall that heat transfer to complete the evaporation would be made impractically. Combined with this difficulty, at low volumes in a normal reactor stirring becomes ineffective. Thus solvent replacements must be done without completely removing the liquid phase at any point.Kilomentor goes on to describe the various less well-known azeotropes within typical solvent swaps -- bet you didn't know that "An azeotrope exists between IPA and EtOAc with bp 74.8 C and composition 77% ethyl acetate and 23% IPA."
The amount of time required to perform a solvent swap on scale can be frustrating to a plant manager or owner -- think about the amount of time you spent in graduate school, rotavapping, rotavapping, rotavapping. Crystallization out of the reaction solvent is a better technique to hope for -- but sometimes, vacuum distillation of 1500 gallons of methanol is going to happen, whether you like it or not. Sigh.