Job posting: process chemist, Abide Therapeutics, San Diego, CA

Via random clicking, a position with Abide Therapeutics in San Diego, CA:

Process Chemist:  

Description: The successful candidate will optimize the synthesis of potential drug candidate molecules directed toward the inhibition of serine hydrolases and function as part of a cross-disciplinary team to advance compounds into clinical trials. The candidate will execute process chemistry optimization of synthetic routes to lead molecules in addition to preparation of novel building blocks and key intermediates on large scale. 

The successful candidate will participate in discussions with contract manufacturing organizations (CMO) to enable the preparation of compounds for preclinical and clinical evaluation on multi-kilogram scale. Additionally, the candidate will engage in pre-formulation activities for lead molecules and early development of solid oral dosage forms. The successful candidate will also contribute to preparing the CMC section of IND applications and investigational medicinal product dossiers in collaboration with consultants, QA specialists and CMOs. 

The chemist will work independently, use databases and information tools to keep current with process chemistry trends and contribute to patent applications and publications. 

Experience and Education Requirements: 

• BS/MS in Organic Chemistry with 5-7 years experience in the pharmaceutical industry
• Experience with process chemistry, scale-up and cGMP principles; pilot plant experience a plus
• Experience interacting with CMOs
• Experience advancing compounds from discovery into Phase 1 clinical trials...

Click here for full listing. Best wishes to those interested.