Sunday, September 27, 2009

Department of Awful Statistics: The September Swoon in CEN industrial job ads

In the past month, there have been 2 (count 'em -- 2!) industrial job ads in Chemical and Engineering News. To see if this is an anomaly or a trend, I've charted the industrial ad content for the issue of C&EN for 2nd week of September. (I tried to pick the issue that was closest to the arbitrary date of Sept. 14.) The resulting graph (data set here) is not encouraging:



Now, there are any number of explanations:

Competition against C&EN: 1989 is before the internet - I'm going to guess that it was the only game in town, if you wanted to hire chemists. Nowadays, it's one of at least 5 or 6 places to go -- besides, who wants to pay for ads on-dead-tree when you could pay much less for ads online?

Recruiters moving their schedules: It's completely possible that companies have, over the years, quit advertising for positions during the 2nd week of September and they're putting their ads in C&EN some other time.

The golden years are over: Perhaps this is evidence of a "secular trend", as the economists would put it, where the job market for chemists is just never going to be as good as it ever was. Sad, if true.

I'm sure there are alternate explanations; readers, you're welcome to comment on them. But nevertheless, the current paucity of industrial job ads and positions is hitting chemists hard.

UPDATE: Clarified a few words here and there. (9/28/09, 6 PM)

Chemjobber C&EN Index: 9/21/09

Industrial positions (non-academic, non-governmental):
Total number of ads: 0
- Postdocs: 0
- Permanent positions: 0

- Ratio of US/non-US: 0/0
Area: 0
Week to week trend: Flat.

Governmental positions (US, international):
Total number of ads: 1
- Postdocs: 0
- Permanent positions: 1

- Ratio of US/non-US: 1/0
Area: 67
Week to week trend: Stable. 

  
Academic positions:
Total number of ads: 29
- Postdocs: 2
- Tenure-track faculty: 35++

- Temporary faculty: 0
- Lecturer positions: 0
- Staff positions: 0
- Ratio of US/non-US positions: 33+/4+

- Area (square cm): 1777
Week to week trend: Down, but strong 

Dude, where's my no-jobs senryu?: 

Unemployment stinks
Post-docs are not much better
Who will hire chemists?


Tenure-track, however...: Again, lots of new tenure-track positions. Good luck out there. 


Small college of the week: Dickinson College (Carlisle, Pennsylvania, student population: 2,300 - SA-LUTE!) is looking for a professor of biochemistry. Among the famous alumni, the fifteenth president, James Buchanan. Wonder what he'd think of biochemistry? (He wouldn't -- he's dead. -ed.)

Friday, September 25, 2009

Daily Pump Trap: 9/25/09 edition

Good morning! Including September 16, there have been 188 new positions posted on the ACS Careers website. Of those, 26 (14%) are faculty positions and 119 (63%) are from our friends at KSR.

The middle aisles smell so fresh!: Want to make processed foods that will make the health nuts scream and mouths water? International Flavors and Fragrances needs B.S./M.S. chemists in their flavor/fragrance delivery research teams. 

Great name: Smooth-On needs a senior polymer chemist; they would like a B.S. chemist with at least 7 years experience.

Gas card no longer needed?: Exxon-Mobil is looking for a fuels researcher; they would like someone who has a fuel chemistry speciality and preferably a Ph.D. in chemistry or chemical engineering.

Postdoc at the aquarium: Sounds like an album name, doesn't it? Monterey Bay Aquarium Research Institute has postdoctoral fellowships open. 'Twould be a lovely place to do a postdoc, wouldn't it?

Kelly Time!: All together now: are you a chemist? Do you like doing chemistry? The geniuses at Kelly Scientific Research would like to know if you can do the following things: be a biostatistician, a "skill [sic] marketing job" with a Ph.D. in plant ecophysiology, a clinical psychologist or a coding nurse. Good luck!

Tuesday, September 22, 2009

Chemjobber C&EN Index: 9/14/09

Industrial positions (non-academic, non-governmental):
Total number of ads: 0
- Postdocs: 0
- Permanent positions: 0

- Ratio of US/non-US: 0/0
Area: 0
Week to week trend: Down.

Governmental positions (US, international):
Total number of ads: 1
- Postdocs: 0
- Permanent positions: 1

- Ratio of US/non-US: 1/0
Area: 67
Week to week trend: Up, slightly. 

 
Academic positions:
Total number of ads: 28
- Postdocs: 3
- Tenure-track faculty: 30++

- Temporary faculty: 0
- Lecturer positions: 0
- Staff positions: 0
- Ratio of US/non-US positions: 31/2

- Area (square cm): 2025
Week to week trend: Up.  

Time again for senryu (since no industry ads): 
CJ sings the blues
Where are the jobs for his friends now? 
Please not more post-docs!

On the other hand...: Plenty of faculty positions to apply for, with 31 faculty positions. 


Small college of the week: The University of Wisconsin - Oshkosh (Oshkosh, WI, student population: 12,669, SA-LUTE!) is looking for a tenure track assistant professor position in analytical position. Doyle Redland (of Onion fame) is a (fake) alumnus, if that's a plus for you.  

Chemjobber C&EN Index: 9/7/09

Industrial positions (non-academic, non-governmental):
Total number of ads: 2
- Postdocs: 1
- Permanent positions: 3+

- Ratio of US/non-US: 1/3+
Area: 76.7
Week to week trend: Up, slightly.

Governmental positions (US, international):
Total number of ads: 0
- Postdocs: 0
- Permanent positions: 0
- Ratio of US/non-US: 0/0
Area: 0
Week to week trend: Down.
 

Academic positions:
Total number of ads: 72
- Postdocs: 5+
- Tenure-track faculty: 78 (6+)

- Temporary faculty: 0
- Lecturer positions: 2
- Staff positions: 1
- Ratio of US/non-US positions: 83/3
- Area (square cm): 3574

Week to week trend: Not applicable.



Piddling: Looking for an industry job? Unless you're heading to South Korea or you want to postdoc, no dice.

Big week for faculty positions: Over 70 tenure-track faculty positions. I think I'll have a more detailed roundup later this week, but it's pretty huge. As I recall, this is the "academic recruiting" issue; nice to see that there's something out there.

Small college of the week: The University of Toronto - Mississauga (Mississauga, Toronto, Canada - student population: 8762) is looking for a Lecturer in Analytical Chemistry. If you want to watch the Toronto Argonauts practice (this is the site of their practice facility) in your off hours, this position might be for you!

Friday, September 18, 2009

Interview: CJ speaks with Dave Harwell on ACS Careers and the ACS Careers website


With my recent complaints about ACS Careers (and Kelly Scientific), I decided to contact them. Dave Harwell is assistant director of ACS Careers and Diversity Programs; it should be noted that he is not speaking here for ACS. Dr. Harwell kindly agreed to an interview by e-mail; below is our exchange on the inner workings of ACS Careers, the ACS Careers website, Kelly Scientific and when he thinks the job market might pick back up. (His answers have been lightly edited by me for links, etc.)  

CJ: How can ACS members interact with ACS Careers staff? What are common complaints, etc.? What are things that ACS members really appreciate?


DH: The easiest way for ACS members to contact the ACS Careers Staff is by writing to careers@acs.org


The Careers Team receives both positive and negative emails from members and other job seekers.  Negative emails are generally focused on the frustrations associated with the job hunt.  People may want more job listings in a particular job category, salary range, and/or geographic region.  Where possible, we try to accommodate these requests by contacting employers with corresponding listings.  However, the reality is that we cannot manufacture jobs.  In the end we are limited by market demands. 


Thank goodness, we also receive thank you notes.  Helping people find employment, especially in a tough economy, is a hard job.  Still, it is rewarding to know that you are able to help in some small way in the process.  Thank you notes generally focus on the services provided by our volunteer career consultants or the resources provided through our website: www.acs.org/careers.  We also receive many positive comments through the ACS Careers Blog and the ACS Careers Industry Forum. 


What would ACS Careers staff most like to hear about/from ACS members? 


I would most like to know about what works.  How are others overcoming barriers and finding opportunities?  The most powerful thing about an association is the ability to share information.  If we are able to find out about strategies that worked for the job search process, we can communicate them to others through our blog and/or the ACS Network.  Most recently, one of our career consultants wrote a knol about the many ways that Google tools can be used in the job search process.  Her knowledge has proven useful to many others, and her knol has become one of the most searched career resources at Google. 


I also want to know about things that are going wrong.  Our team can’t fix a problem unless we know it exists.  Recently, Chemjobber alerted us to a phishing scheme in the jobs database.  We were instantly able to pull down the listing and work with our vendor to enhance our restrictions and firewall protections. 


Our mission at ACS Careers is to help ACS members gain employment; to help them keep their jobs; and to prepare them for the many career transitions that they are bound to face.  Any communications that helps us to further our goals are welcomed and encouraged. 


Are there any efforts by ACS Careers to expand their web presence? The RSS feed is handy. 


Yes, we are constantly developing new resources and making them available through our websites.  Our greatest challenge at this point is integrating the websites that we currently provide.  Our job listings and career consulting services can be found through the jobs database site (chemistryjobs.acs.org), while most of our career resources are located at www.acs.org/careers.  We also have online and facilitated learning opportunities through the ACS Center for Professional Development and the ACS Professional Training websites.  And lastly, the ACS Careers Blog is located at acscareers.wordpress.com


Most recently, we added the first in our Career Caffeine video series.  This first video focuses on the job search process.  Two more videos are in production for the topics of writing a resume and interviewing.  Self study guides and group discussion guides have also been developed for the job search, resume writing and interviewing processes.  All of these resources are available through the Job Search Essentials page on www.acs.org/careers


What is the process for getting an ad on ACS Careers? 


For a job listing, employers use an automated system very similar to the one used by job seekers.  The potential employer creates a profile for the company and enters the text for their advertisement.  They also select appropriate categories for the job such as inorganic, green and/or senior level.  To post the job listing, they choose a term of service and either pay by credit card or choose to be invoiced.  The fees generated through this process help pay for services offered to our members.  The fee structure also helps to ensure that job listings are legitimate. 


Although ACS charges employers for job listings, there is no charge to job seekers for any of our services. 


Are ads vetted by an editor before posting? 


Listings that are published in C&EN undergo review before publication; however, online job listings generally do not.  The online job posting system is automated in order to keep the posting process timely.  Employers generally expect their job listings to be posted as soon as they complete the e-commerce process. 


If complaints about a listing are received, the posting is reviewed immediately and it may be removed or modified at the discretion of ACS staff and legal counsel.  In cases where illegal or questionable activity is detected, listings are removed and employer profiles are blocked to protect our users.  Our service provider, Boxwood Technologies, also monitors postings and traffic patterns to detect illegal activity.  All user records are protected in accordance with the highest industry standards including PCI compliance. 


What is the relationship between Kelly Scientific Resources and ACS Careers? Do they pay for ad space? 


The ACS Committee on Economic and Professional Affairs recognized the only way to apply for entry-level positions at many chemical and pharmaceutical companies is through staffing or placement agencies.  Some companies, especially larger ones, have outsourced their screening and on-boarding processes to professional staffing agencies.  The Committee recommended that ACS develop relationships with one or more staffing agencies in order to provide a route into entry-level positions at major chemical and pharmaceutical companies.  Negotiations were begun with several firms; however, Kelly Scientific Resources was the only staffing agency who both applied and was able to meet all of the requirements set by the Committee in terms of hiring and compensation practices. 


Kelly Scientific Services pays an annual fee to ACS to place their job listings within the ACS Careers Jobs Database.  They also provide job placement and career counseling services to ACS members upon request.  Additionally, they provide informational seminars at ACS national and local meetings as requested. 


What's your prediction for when the job market for chemists will pick up? Any 'green shoots' that you're aware of? 


I must preface this answer by stating that I am not an economist.  I am a chemist.  I must also state that this is my own opinion and it does not reflect the views of the Society.  It should not be used as the basis for any financial or other transactions. 


Today’s Financial Times has a story on the cover which quotes Ben Bernanke, US Federal Reserve chairman, as stating that the US recession “is very likely over,” but I think that it will be six to eight months before we will see changes in the US chemical and pharmaceutical job markets.  Most chemical companies are still highly leveraged with large inventories on hand.  They are not likely to start hiring again until those inventories are reduced and production starts.  The pharmaceutical industry does not have the same problems with regard to inventory surpluses, but their hiring practices have also slowed due to mergers and acquisitions (M&A).  The M&A process generally takes one to three years to complete.  During the first year, there is generally no hiring and layoffs are common due to the elimination of redundant positions.  The good news here is that we are about 6 to 8 months into the very large M&As of 2008 and 2009.  The job market for chemists should start to thaw next spring.  In the mean time, we may see additional layoffs as companies compensate for poor market performance and those involved in M&A continue to eliminate redundancies.

Tuesday, September 15, 2009

Daily Pump Trap: 9/15/09 edition

Good morning! Including September 11, there have been 104 new jobs posted on the ACS Careers website. Of those, 58 are from our friends at KSR and 28 are academic faculty positions.

There they go again!: Genentech is looking for B.S. or M.S. synthetic chemists for their medchem program. I feel like they've done this before, but hey! it's the Bay Area. Good luck!

Tasty: ICP in St. Louis, Missouri, is looking for a Ph.D. chemist with experience in inorganic chemistry to come up with applications for food phosphates. Interesting...

Like organizing?: Targacept (of our last DPT) is looking for a B.S. chemist to be a compound management scientist. I would imagine that the folks who like these positions are very neat (said the person with the messiest desk in the company...)

There's the stimulus!: The National Renewable Energy Laboratory is looking for a M.S. chemist to apply NMR technology to biomass conversion. That's a little unexpected, but it sounds cool.

Kelly Time!: Say it with me, folks: are you a chemist? Do you like doing chemistry? Kelly Scientific Resources wishes to know if you'd like being a registered nurse or perhaps a manufacturing operator. Sigh.

Saturday, September 12, 2009

Department of Awful Statistics: tough times at Harvard, too

How's this for a bit of depressing news? You can find the recruiting schedule for Harvard's Department of Chemistry and Chemical Biology here. Handily, they have the recruiting schedule for the last 3 years, too.

I tabulated the schedules here* and came up with this little graph you see above. That's the ugly truth, folks. If they ain't hiring folks outta Harvard, they're not hiring anywhere. Let's see where we get in 2010 -- remember, unemployment is a lagging indicator.

*I know this isn't by any means scientific. Also, I didn't count companies that were visiting, but only gave a presentation and did not interview. I suspect the 2006 stats are less detailed (i.e. there may have been companies that presented, but did not interview.)


UPDATE: A commenter notes that the 2009 schedule ended with 12 companies visiting; still, that's less than 2008. (Man, I wish that weren't the case.)

Friday, September 11, 2009

Daily (?) Pump Trap: 9/11/09 edition

Good morning! Since September 1, there have been 191 new jobs posted to the ACS Careers jobs database. Of those, 49 are from our friends at Kelly Scientific Resources.

Do you want to be a professor?: There have been 77 faculty positions posted in the last 11 or so days. That's remarkable -- I imagine it's also going to be a healthy sign for the academic recruiting issue of C&EN. Good luck, postdocs.

For the rest of us: Bugs, polymers and fuel cells -- that's what Lawrence Berkeley Labs is looking for in a Ph.D. chemist staff scientist. If electrochemistry is your field, this may be a job for you.

That's an interesting combination: Sandia National Labs is looking for a B.S. chemist to help with computer modeling in biofuels and neurosciences. I'm guessing those are the folks who are funding the position? "Hyperspectral Imaging" -- sounds very Star Trek, doesn't it?

Inorganic chemist wanted, real science wanted?: Blacklight Power (home of the "hydrino") is looking for a Ph.D. inorganic chemist. I'm pretty skeptical of their science, but they're hiring, I guess.

Must love college basketball: If you're a B.S. analytical chemist with 6 years of experience (or a M.S. with 2) in HPLC analysis, there's a job in North Carolina for you with Targacept.

Kelly Time!: Are you a chemist? Do you love doing chemistry? The geniuses at Kelly Scientific Research want to know if you can be a "psychometrician rater", a pharmacist or a entry level microbiologist. Sounds like a good fit for me!

While I won't get off my KSR hobbyhorse anytime soon (considering they make up 26% of the take from ACS Careers), I have noticed that their postings are becoming more relevant as of late.

Thursday, September 10, 2009

Chemjobber C&EN Index: 8/31/09

Industrial positions (non-academic, non-governmental):
Total number of ads: 0
- Postdocs: 0
- Permanent positions: 0
- Ratio of US/non-US: 0/0
Area: 0
Week to week trend: Flat, like Kansas.

Governmental positions (US, international):
Total number of ads: 1
- Postdocs: 0
- Permanent positions: 1
- Ratio of US/non-US: 1/0
Area: 40
Week to week trend: Down.

Academic positions:
Total number of ads: 22
- Postdocs: 0
- Tenure-track faculty: 26
- Temporary faculty: 0
- Lecturer positions: 0
- Staff positions: 0
- Ratio of US/non-US positions: 24/2
- Area (square cm): 967

Week to week trend: Down, slightly.

Time for poetry:
No industry ads
Where will workers find jobs now?
Not C&E News.

Nevertheless: There are a goodly number of tenure-track positions available. All of these university postings make me wonder how big the university recruitment special issue will be...

Small college of the week: Mt. Holyoke College (South Hadley, MA, student population: 2,100 - SA-LUTE!) is looking for a tenure-track assistant professor who has a speciality in either bioorganic or biophysical chemistry. That sounds fun to me.

Thursday, September 3, 2009

Chemjobber C&EN Index: 8/24/09

Industrial positions (non-academic, non-governmental):
Total number of ads: 0
- Postdocs: 0
- Permanent positions: 0
- Ratio of US/non-US: 0/0
Area: 0
Week to week trend: Flat as a pancake.

Governmental positions (US, international):
Total number of ads: 1
- Postdocs: 4
- Permanent positions: 4
- Ratio of US/non-US: 8/0
Area: 473
Week to week trend: Up, big.

Academic positions:
Total number of ads: 25
- Postdocs: 0
- Tenure-track faculty: 42+
- Temporary faculty: 0
- Lecturer positions: 0
- Staff positions: 0
- Ratio of US/non-US positions: 23/19
- Area (square cm): 1207
Week to week trend: Up, big.

Not a good week to be looking for an industry job: De nada.

But if you're looking for a faculty position: There's 42 new positions posted this week, including the University of Miyazaki's ten assistant professor positions. Good Lord, that's a lot of professorships. Best of luck, folks. (That Wikipedia entry explains it -- they've been a chartered university for 5 years. Nothing like getting in on the ground floor!)

Small college of the week: The University of Southern Maine (Portland, ME, student population: 10,974 - SA-LUTE!) is looking for a tenure-track assistant professor in biochemistry. Like lobster? This position might be for you!

Tuesday, September 1, 2009

Daily Pump Trap: 9/1/09 edition

Good morning! Including August 22, there have been 167 new jobs posted on the ACS Careers website. Lots of odd jobs, not so many permanent positions.

Aloha!: Are you an analytical chemist? Want to move to Hawaii? Cellana LLC is a company doing biofuels work and they're looking for an experienced chemist to do chromatography (PhD preferred, BS chemists welcome to apply.)

Computational chemist desired: Cubist Pharmaceuticals is looking for a PhD computational chemist with 5-7 years of experience. Sounds like a company on its way up, with a couple of products under its belt.

There's our stimulus funds!: Argonne National Labs is looking for a PhD electrochemist to do studies on lithium ion batteries. I think it's a good time to be a battery specialist -- what do you think?

Do you get discounts on contact solution?: Alcon is looking for an experienced analytical chemist to support a surgical R&D team. Sounds pretty cool. M.S. or Ph.D. with experience desired.

Kelly Time!: Are you a chemist? Do you like to do chemistry? Kelly Scientific Resources wants to know if you are a bilingual nurse, can do biostatistics calculations or if you want to leave the bench to be a procurement manager. Awesome!

Thursday, August 27, 2009

~25% of Harvard PhD chemists go to Wall Street?

Ezra Klein of the Washington Post has a post on a Harvard economist's article about how the top-end salaries of the financial sector were pulling the brightest students towards Wall Street. Klein writes about the smart young folks who become financial wizzes:

If the financial sector is somehow shut down, or radically shrunk, they'll just go to the next most profitable industry. Doctors get paid a lot, but there are sharp constraints on supply, so you'd just have more competitive medical schools, as opposed to more doctors. We'll have a lot more lawyers. Many more management consultants. Potentially more engineers and researchers, though those gigs require specialized graduate education -- frequently in the hard sciences -- and I'd imagine there's not too much overlap between college kids interested in organic chemistry and college kids who end up in finance at 23. (emphasis CJ's)
And in the comments, a Harvard chemist (Ph.D.?) (post-doc?) sez:

As a former organic chemistry graduate student, I can say that finance/ consulting are hugely popular alternatives to academia/pharmaceutical research. I think about 25% of PhD students went in to consulting from the Harvard chemistry department during the years that I was there (2005-2008) (emphasis CJ's), and McKinsey had a very strong recruiting presence, which made it seem that consulting was the main alternative to a lab based research career.
Twenty-five percent? One in four? This can't be right, can it? Those who've been around Harvard folks or in the department itself -- is this true?

Frankly, I don't really have a problem with this, but it does seem a waste of NIH funding (where the taxpayer gets the public domain science and the trained scientist, too.) Readers, what say you -- true or just a bit of blog comment hyperbole?

UPDATE: I e-mailed a knowledgable insider who replied as such (answer slightly redacted for privacy):

I don’t know the numbers for the department, but I can tell you from my lab, the number of graduate students who have graduated in the past four years who went into business consulting was [above 25%.] I know of plenty of other students from the department who have taken the consulting route (including the author of the original comment, I think), so if 25% is an overestimate, I don’t think it’s far off.

I’ll leave the interpretation of these data to you. From an inside perspective, these people were very different from each other, and I can’t identify a common reason for their leaving research. Interestingly, I don’t know of a single postdoc from our lab (or others, for that matter) who has gone into consulting.
Wow -- that's remarkable. I'm guessing that this is something that's H-bomb related; I can't imagine greater than 10% of a PhD graduating class of most other top flight programs going to business consulting.

Chemjobber C&EN Index: 8/17/09

Industrial positions (non-academic, non-governmental):
Total number of ads: 0
- Postdocs: 0
- Permanent positions: 0
- Ratio of US/non-US: 0/0
Area: 0
Week to week trend: Down, big.

Governmental positions (US, international):
Total number of ads: 0
- Postdocs: 0
- Permanent positions: 0
- Ratio of US/non-US: 0/0
Area: 0
Week to week trend: Down.

Academic positions:
Total number of ads: 18
- Postdocs: 3+
- Tenure-track faculty: 14
- Temporary faculty: 0
- Lecturer positions: 0
- Staff positions: 2
- Ratio of US/non-US positions: 19/0
- Area (square cm): 455
Week to week trend: Up, slightly.

Tough week, huh?: No industrial positions this week. No governmental ones, either. Sorry, folks. Great week for academic positions, though, with a few small-college positions available. Over to you, Adam!

This'll be good: The next "Employment Outlook" issue will be November 2nd. Any chances for a huge week of recruiting then? Please?

Small college of the week: Hope College (Holland, MI, student population: 3,200 - SA-LUTE!) is looking for a tenure-track assistant professor in inorganic chemistry. A lovely town, Holland, Michigan, but if you're allergic to tulips or those funny wooden shoes, I'd suggest you apply elsewhere...

Wednesday, August 26, 2009

Chemistry in the desert: life at China Lake



Photo credit to B.L.

I posted a bit on one of the recent DPTs about working at China Lake, which is one of the US Navy's weapons-related scientific research labs. A poster wrote in and said that they worked there; we'll call this person B.L. Below are a few questions with B.L. about life doing a postdoc for the US Navy; B.L.'s answers were lightly edited for clarity and checked for accuracy.

CJ: What was your background? What did you do, scientifically, out there at China Lake?

My background was actually organometallics for my Ph.D. followed by a first postdoc in organic methodology. China Lake was my second postdoc. What I did there was actually to work on "n-doping" conducting organic polymers which would be used as the anode in a polymer-based supercapacitor (lightweight battery replacement!). The chemistry involved lots and lots of pyrazine cheimstry - which I had never done before - so I didn't have a whole lot of success. The real pity is that the project was my own idea...I of course worked on synthesizing other heterocyclic systems when the pyrazines didn't work out.

What is it like to work at a government lab? How is it different than an academic one (or an industrial one?)
Hmm. Now that I've been in all three types, I can say the major areas of difference are in safety and in instrumentation. As we're all painfully aware, safety in academia is pretty much up to you - nobody tells you to do much of anything. In industry, believe me, if I so much as appear without a lab coat on I hear about it. To say nothing of the public mea culpas and detailed analysis of anything defined as an "incident" that I have to go through if, god forbid, I have an actual incident in the lab. And an "incident" may be as simple as blowing my reaction through my condenser (whoops) or cutting myself on glass.

At China Lake, at least, it's a little bit in between for safety. No one made me wear a lab coat, but they didn't want you to even think about working alone. No after hours reactions unless you could find someone else on the wing and tell them what you were doing. If you blew your reaction through your condenser, nobody really noticed, but on the other hand, if you had even a minor detonation, it was a very serious thing, involving a very similiar process to the public mea culpas, detailed analysis, etc., etc. that I deal with in industry.

One thing at China Lake that was very cool was the emergency system. If you felt threatened for any reason you could run to the hallway and hit an emergency button that simultaneously put all the hoods on overdrive, sounded an alarm, and set emergency lights flashing. From a chemical point of view this might only be useful to keep contamination from spreading from the one affected hood, but really it was there to let everyone know that someone was in trouble. This was used several times during my one year there, and let me tell you, it was effective. So yeah, at the one government lab I've been at safety was maybe not quite as rigorous as at the industrial lab I'm in now, but I think you'll be safe nonetheless.

From the instrumentation point of view, in academia anything you will reasonably need or want is there, but you have to learn to use it yourself at great expense in time. In industry, at least where I am now, we have everything I could want and there's a dedicated staff of skilled technicians who carry out all analyses for me (this is ideal). At China Lake, they have everything you could reasonably want but you'll have to learn most of it yourself again - although for some instruments there are staff members who will do it for you. Also, for certain projects they have extraordinarily awesome and expensive instruments - probably not for your project though (tough).

Who was your supervisor (i.e. a naval officer or a civilian scientist?)

My supervisor was a civilian scientist, and that's pretty much how it goes at China Lake! Your boss may have a deep security clearance, but he or she will not have a rank, serial number, and a buzz cut. The R&D employees there are pretty much 100% civilian.

Did you feel that it was a true "post-doc", in that there was a scientific project that you were responsible for driving forward?
Absolutely. In order to get the postdoc positions advertised, you'll have to be awarded a fellowship and you'll have to go through the usual fellowship application process (as you'll find out when you send in an application. They are typically funded through a DC based outfit call the American Society for Engineering Education). When I was writing my fellowship application, my future boss gave me the project background and a few suggestions and then I had to hash out the rest myself. I had an original idea, a well-thought out method of getting to my target compounds (I thought), and that was the project I was responsible for pushing forward. Well, changing fields almost 100% may look OK on paper, and it didn't really work out in the lab, but my original proposal was what I was sinking or swimming with.

What was it like to interact with the military folks?
The only interaction I had with military personnel was showing my badge at the entrance gates! I never saw anyone in uniform wander down our wing (unless it was by accident). For the most part, military higher ups didn't get involved until field testing stages, which I never had anything to do with.

If it was synthetic chemistry, what is it like to do synthetic organic chemistry on explosives?
Ah, no explosives here. However, I shared a lab with Robert Chapman (who will be some lucky applicant's supervisor on the explosives research project). Bob did things in the lab on a very, very small scale. In fact, he typically used unstabilized methylene chloride as solvent - because the stabilizer would mess up his NMRs after he was done with his syntheses! So, minimal danger level there. When he was scaling up he would use a totally different building - I saw him once walking around with the really thick overhead stirrer shafts, so I can only imagine about the safeguards involved in that facility.

Where are you now? How did your naval postdoc help or hinder you?
I am out in the big wide world of industry now, and I have been for the last four years. I'm obviously not in pharma given my pedigree. I have to say that I think the naval postdoc helped, if only a little bit. Remember, you need to win a fellowship to go there, and that only looks good on the resume. Now, if you were interested in working on esoteric military-based materials problems, you should definitely go. Go now. (Emphasis CJ's.) When I met the division director at China Lake, the first thing he told me is that it was possible to become staff from being a postdoc there. One of my postdoc friends from China Lake is currently (unbelievably well remunerated) staff at Edwards AFB. People have jumped between China Lake and Los Alamos. So if you are interested in military stuff it is a foot in the door.

A few more things: The research projects at China Lake are entirely devoted to the needs of the Navy. This means that really big important projects there will be all about stuff that you probably never thought of....This also means that everything you work on may end up on either a warship, a fighter plane, or a missile (China Lake is home of the Sidewinder missile, and also all of the US Navy's missile testing program, as you will quickly find out if you end up going there). For an example, one of the things reaching the field testing stage when I was about to leave was an organic polymer intended to replace chromium-based anticorrosion primer paints. This project was a big, big deal. Also just as I was leaving a call went out for proposals for a lead-free solder. These were both environmental-based issues, but even my early stage project for lightweight battery replacements was intended to lighten...missiles. Missiles need batteries too, and the engineers decided that lighter batteries would increase performance by a non-trivial amount.

Another thing to remember is that they actually want to publish as much as possible at China Lake. The defense granting agencies treat applicants a lot like the more academic institutions in using publications as a sort of judgement mechanism. So if at all possible, your research will not disappear down a black hole. There was also a really cool division of patent royalties, in the unlikely event that you work on a real hit, you may one day see some real money.

About living in Ridgecrest: Well, the location is not good. It's in the middle of the Mojave desert. The view from my living room was nothing but red rocks, dirt, and creosote bushes right up to the horizon. I didn't like it, one little bit. However, management there knows it sucks, and they try hard to make it better. We all had "flex-time" whereby everyone worked an extra hour for nine work days, and then every other Friday was off. But, no one really cared if you worked that extra hour every day...so, 26 extra days off per year. The $50,000 stipend will cover nearly anything you could want out there. My 2-bedroom apartment went for the princely sum of $450 per month. Really, just don't buy a new Corvette and money will be no problem.

And yeah, you're at least three hours of frantic freeway driving from anywhere...but even so, at times the basic weirdness of it all is really entertaining. I remember cradling a length of threaded pipe capped at both ends bearing a label of "Sarin" in one of the stockrooms (CJ: !!!)....I'll never do that again....so, yes, if you want something different you might consider it.

Sunday, August 23, 2009

ACS Careers gets punk'd


Checking the ACS Careers jobs feed, I noted a new job posting for "jokina", which is apparently a "top job search engine." When you click on the posting, the job description says "Employment, USA Jobs, Job Search, Jobs Part Time & Student Summer Jobs. http://EasyJobsFree.com"

This last leads to a website that is clearly some sort of spam site about working 4-5 hours a day for 5k a month.

You know, I'm beginning to think that there's someone asleep at the switch over there at ACS Careers (or actually, they need to change their filtering software.) I'm going to e-mail folks at ACS and see if I can get a response.

Interview: what's it like to handle lots of nBuLi?

Commenter extraordinaire CMC guy recently commented on his experience performing larger-scale reactions with nBuLi. I asked CMC guy to answer a few questions about these reactions and he kindly agreed; his answers to my questions were lightly edited for clarity.

CMC guy's disclaimer: Observations from (former?) Process Chemist who’s been away for the bench for several years yet still directly oversees API R&D and Manufacturing (so on occasion I can pretend I still am a Chemist). The usage of BuLi mentioned was at least 15 years ago so certain details are lost to memory, or perhaps would be confidential even if I did fully recall, yet I can speak to some elements and trust will answer/illustrate features of larger scale chemistry (in context mainly of Pilot Plant).

CJ: What did you do different than a typical run in a lab?

Scale was 50-100x of largest lab runs so were many both direct and subtle differences typical of such efforts. Everything was “planned” in detail from lab experiments, available reagents (10N nBuLi) and multiple pre-campaign meetings to discuss and refine, particularly how to execute most safely. Procedure was codified and captured stepwise in Batch records, not recorded after the fact. Because usually reactors have only a sight glass port did not always have visual clues normally used in lab but had alternative monitoring (internal temp, pressure, sample testing) to reaction. We also had at least 2-4 people involved during operations, mostly lost PhDs and Chemical Operators who knew their stuff, particularly during hazardous portions. Weight of materials was used to measure quantities rather than doing by volume.

CJ: How'd you get the BuLi into the reaction?

Method analogous of “cannulation” commonly used in lab with the BuLi coming in canisters with valve ports, like heavy duty propane tanks, and used N2 pressure to push transfer (10N nBuLi a viscous solution whose behavior reminded me of tBuLi/Et2O which is more intense flammability than 1-2.5 N BuLi most people familiar with). The connections/plumbing not too different from gas cylinders with Teflon lined stainless steel flex transfer tubing (<1/2> 5L run went directly into reaction in stop/go pulses based on maintaining temperature control (keep between -40 to -20°C). The 20L amounts was placed in a drop tank, thinned with solvent (THF or DME) then added “dropwise” for smoother operation (and worked better since less manipulation of BuLi. N2 Purges were enhanced to assure continuous inert atmosphere. Post reaction we did breakdown and clean externally with CO2 saturated solvent (IPA?) wipes and tubing was sealed in bags then treated in same fashion in a lab hood.

CJ: What kind of PPE is needed for that scale?

Pilot Plant normally has many established Engineering controls for safety with alarms, suppression systems and hand extinguishers readily available. Clothing worn was not drastically different with lab coats or uniforms except hardhats/safety glasses were all mandated (and was strictly enforced well beyond lab). Gloves (nitrile-type mainly) and maybe rubber aprons, then face shields were used when connecting or adjusting values and the BuLi cylinders were placed behind a blast shield (lab type). One person always stood at distant watching and holding a fire extinguisher when handling the BuLi directly..

CMC guy's concluding comments:

A general remark, although it would seem obvious, in that Process Development/Scale-up pretty much always has inherent dangers because of the larger amounts involved and when utilize particularly hazardous agents this increases dramatically, therefore if some thing were to go wrong the potential damage would be much greater (however seen many new PhDs who have to be educated in this aspect because of bad habits picked up in grad school.)

Note that Costs correlates this same way as mistakes during scale-up can be extremely expensive so reinforces the overall awareness necessary. One hopes because of this risk factor process chemists become highly safety conscious in everything that they do but as it typically pertains to Pilot Plant Operations requirements create a very different environment from Labs. The basics distinctions between Lab vs. Scale-up arenas I would summarize as fall into Planning, Equipment, Personnel and Enforcement (of Policies).

Friday, August 21, 2009

Daily Pump Trap: 8/21/09 edition

Mornin', folks. Since August 11, there have been 170 new jobs posted.

Workin' for the complex: SAIC (a major, major defense contractor) is looking for a Senior Scientist to do work in NCI's Developmental Therapeutics program in fungal natural products. Awesome.

Is there an electrochemist in the house?: DOE is looking for a senior electrochemist to lead their electric battery team. For the good of the country, I hope they get someone good.

Really workin' for the complex: The Navy's looking for a couple of postdocs to do inorganic/organic synthesis, with an eye towards explosives. If you take these positions, hope you like it dry.

Kelly time!: Are you a chemist? Do you want to do chemistry, maybe in a lab? Kelly Scientific Resources and the American Chemical Society want to know if you're interested in being a master's level molecular biologist, having a RN's license, looking after animals or working in a chicken vivarium!

ACS powers-that-be: I'm not going to quit on this.

Chemjobber C&EN Index: 8/11/09

Industrial positions (non-academic, non-governmental):
Total number of ads: 2
- Postdocs: 0
- Permanent positions: 6+
- Ratio of US/non-US: 3+/3+
Area: 515
Week to week trend: Up.

Governmental positions (US, international):
Total number of ads: 1
- Postdocs: 0
- Permanent positions: 1+
- Ratio of US/non-US: 1+/0
Area: 157
Week to week trend: Up.

Academic positions:
Total number of ads: 11
- Postdocs: 3
- Tenure-track faculty: 10+
- Temporary faculty: 0
- Lecturer positions: 1+
- Staff positions: 0
- Ratio of US/non-US positions: 11+/0
- Area (square cm): 449
Week to week trend: Up.

Hi, there, GSK: So GSK put out a full-pager, looking for help in their API and formulating folks. Physical chemists, material scientists, crystallographers and chemical engineers. Good jobs, all. Let's keep it coming and best of luck to GSK, who seems to be prepping for marketable products.

Bold predictions, failed: I coulda sworn the August 10th issue was the big career issue. Maybe it's next week. If it was this week, no good for us.

Eli calls: Big-time group postdocs, Yale is looking for assistant professors to start on July 1, 2010. Good luck, folks. This is one that you want.

Uh, what? And where?: The good folks of the South Dakota State University Biological Control and Analysis by Applied Photonics (BCAAP) are looking for positions in "synthetic and physical organic chemistry, medicinal chemistry and drug delivery for cancer therapeutics; and fluorescence microscopy techniques for analysis of [blah, blah, biology, blah.]" Okay, so get the educational requirements: "earned Ph.D. in biochemistry, biological chemistry, biophysical chemistry or closely related discipline." Hmmm. Hmmm.

How about a degree in um, organic chemistry? Maybe? Kind of like the union electricians' motto, organic synthesis is not a hobby.

Small college of the week: Albright College (Reading, PA, student population: 1,650 - SA-LUTE!) is looking for a inorganic chemistry faculty position. Sounds like a good time -- looks like you'll just a 7 professor department, in the 5th (count 'em, 5th!) largest city in Pennsylvania.