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Further explanation from another commenter:
Has anyone at Pfizer ever played telephone? Physically separating the 'designers' and the 'chemists' by 108 miles is lunacy; sometimes it's occasionally difficult to communicate between two chemists separated by 30 feet (distance from office to lab.) Assuming this is actually happening, this is proof that Pfizer senior management has completely lost their marbles and are just rearranging deck chairs.
Once again, I am reminded of the many, many comments that people have made about what makes a successful drug discovery team (not that I've ever truly been part of one): lots of communication and collaboration (and downtime out-of-meeting talks) between the relevant scientists, both chemists and biologists. I am curious when larger pharma companies will relearn these truths.