Wednesday, April 29, 2015

Internship opportunity: MedImmune, Gaithersburg, MD

From the inbox:
There are a number of bioorthogonal reactions which remain unexplored in the area of Antibody-Drug Conjugates. Studying a panel of unnatural amino acids will expand our understanding of the structure-activity-relationship (SAR) of these amino acids and their corresponding tRNA synthetase, thereby expanding MedImmune’s capabilities to design the next generation of ADCs or other protein conjugates.

The summer intern will synthesize and purify a library unnatural amino acids and fully characterize them by LC-MS, 1H NMR, and 13C NMR. These amino acids will then be analyzed for their incorporation efficiency during protein expression using a high throughput method developed at MedImmune.

At the end of the internship, the student will prepare and present a poster at the intern science fair. In addition, the student will present his/her research during our group meeting.

This paid internship is open to both undergraduate and graduate students. Preferably, the student would have some experience in synthetic chemistry beyond O-Chem lab. 
Interested? E-mail thompsonpam-at-medimmune/dot/com (note spam-proofing)

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