I figured H1B out during a post-doc many years ago when I worked for this douchebag [redacted]. I was the only American, which was fine, I really enjoyed the internationals. However, after a few months of 6x12h days, plus an appearance on Sunday, I had enough. My salary was 23k per year.
The last straw was him berating me for not taking his suggestion of switching the solvent to DMF in making a dianion with NaH and nBuLi. Then he yelled at me for enlisting the help of a graduate student who had nothing to work on. I took the keys to the lab off my keychain and marched into his office and gave him the immortal words of Johnny Paycheck "Take this job and shove it."
I took a few weeks off and went fishing and worked various manual labor jobs and got back in amazing physical shape. I really enjoyed that summer. This was followed by an adjunct stint. I eventually found my way back to a science career, but in a non-traditional path. The thing that struck me the most was the despondency and lack of options of the post-docs who remained. Apparently I was treated well compared to the internationals, or so the American grad students told me. Of course they had to take it, it was not like they could tell him to F off.
There really is a shortage of people who are highly intelligent and well educated in a notoriously difficult discipline who are ready to be treated like excrement on a daily basis for the wages of migrant tomato pickers.A Real American Hero.